Description
Ibandronic Acid Concentrate for Infusions 1 mg/ml. 6 ml
Ingredients
Each ml contains 1 mg of Ibandronic acid.
Mechanism of Action
Ibandronic acid works by inhibiting bone resorption, leading to increased bone mineral density and reduced fracture risk. It is a potent bisphosphonate that specifically targets osteoclasts, the cells responsible for breaking down bone tissue.
Pharmacological Properties
Ibandronic acid is a bisphosphonate that acts by binding to hydroxyapatite crystals in bone, inhibiting osteoclast activity and inducing apoptosis in these cells. This results in decreased bone resorption and increased bone mineral density.
Indications for Use
Ibandronic acid concentrate for infusions is indicated for the treatment of osteoporosis in postmenopausal women. It helps in reducing the risk of fractures and improving bone density by inhibiting bone resorption.
Contraindications
Do not use Ibandronic acid if you have hypocalcemia (low blood calcium levels), severe renal impairment, or a known hypersensitivity to bisphosphonates. Consult your healthcare provider for further guidance.
Side Effects
Common side effects of Ibandronic acid may include gastrointestinal disturbances, musculoskeletal pain, and flu-like symptoms. Rare but serious adverse effects can include osteonecrosis of the jaw and atypical femoral fractures.
Usage Instructions
The recommended dosage of Ibandronic acid concentrate for infusions should be determined by a healthcare professional based on individual patient needs. It is typically administered as an intravenous infusion over a specific period according to the prescribed schedule.
Benefits Compared to Analogues
Clinical trials have demonstrated the efficacy of Ibandronic acid in reducing fracture risk and improving bone mineral density in postmenopausal women with osteoporosis. Compared to other bisphosphonates, Ibandronic acid has shown similar effectiveness with a favorable safety profile, making it a valuable treatment option.
Suitable Patient Groups
Ibandronic acid can be used in postmenopausal women with osteoporosis who are at risk of fractures. It is also suitable for elderly patients who require osteoporosis treatment to maintain bone health and reduce fracture incidence.
Storage and Shelf Life
Store Ibandronic acid concentrate for infusions according to the manufacturer’s instructions. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.
Packaging Description
Ibandronic acid concentrate for infusions is available in 6 ml vials, each containing a concentration of 1 mg/ml of the active ingredient. The packaging should be intact and sealed prior to use.
Clinical Evidence and Proven Effectiveness
Studies have shown that Ibandronic acid is effective in reducing fracture risk and improving bone mineral density in postmenopausal women with osteoporosis. Research published in the Journal of Bone and Mineral Research supports the use of Ibandronic acid in the management of osteoporosis.
