$6.00
Manufacturer: Ukraine
Potassium iodide? Some forms of iodine help your thyroid work properly. Most people get the iodine they need from foods like iodized salt or fish. The thyroid can “store” or retain only a certain amount of iodine. In the event of a radiation emergency, radioactive iodine may be released into the air. This material can be inhaled or swallowed. It can get into the thyroid gland and damage it. The damage probably won’t show for years. Children most often have thyroid damage. If you take potassium iodide, it will fill the thyroid gland. This reduces the likelihood of harmful radioactive iodine entering the thyroid gland.
Description
Iodid Composition
active substance: potassium iodide;
1 tablet contains potassium iodide in terms of dry matter 261.6 mcg and iodine 200 mcg
excipients: lactose, microcrystalline cellulose, magnesium carbonate, sodium thiosulfate, colloidal silicon dioxide, povidone, magnesium stearate.
Iodid Dosage form
Pills.
Basic physical and chemical properties: tablets of white or white color with a yellowish tinge, with a flat surface, scored and beveled.
Iodid Pharmacotherapeutic group
Drugs for the treatment of thyroid diseases. Thyroid drugs. Iodine preparations.
ATX code Н03С A.
Pharmacodynamics
Iodide-Farmak is a preparation of inorganic iodine. Iodine is a vital trace element that is part of the thyroid hormones – thyroxine (T4) and triiodothyronine (T3), which ensures its normal functioning.
When iodides enter the epithelial cells of the thyroid follicles under the influence of the enzyme iodide peroxidase, iodine is oxidized with the formation of elemental iodine. The substance enters into a substitution reaction with the aromatic tyrosine cycle, resulting in the formation of thyronines: 3,5-iodine derivative (thyroxine hormone – T4) and 3-iodine derivative (triiodothyronine hormone – T3). Thyronines form a complex with the protein thyroglobulin, which is deposited in the colloid of the thyroid follicle and remains in this state for several days and weeks. With iodine deficiency, this process is disrupted. Iodine, entering the body in physiological quantities, prevents the development of endemic goiter associated with a lack of this element in food; normalizes the size of the thyroid gland in newborns, children, adolescents and young adult patients; affects the indicators of the ratio T3 / T4, TSH.
Pharmacokinetics
After oral administration, iodine is almost completely absorbed in the small intestine. Within 2 hours after absorption, it is distributed in the intercellular space; accumulates in the thyroid gland, kidneys, stomach, mammary and salivary glands. The volume of distribution in a healthy person averages 23 liters (38% of body weight). The concentration in blood plasma after application of a standard dose is 10-50 ng / ml, while the iodine content in breast milk, saliva, gastric juice is 30 times higher than the concentration in blood plasma. The thyroid gland contains ¾ (10 – 20 mg) of all iodine in the body. Iodine is excreted mainly in urine, to a lesser extent in feces and exhaled air. When the equilibrium concentration is reached, the amount of iodine that is excreted is proportional to the daily intake with food.
Indications
Prevention of the development of iodine deficiency, including during pregnancy or lactation.
Prevention of recurrence of iodine-deficient goiter after surgical treatment, as well as after the completion of complex treatment with thyroid hormone preparations.
Treatment of diffuse euthyroid iodine-deficient goiter in children, including newborns, and adults.
Contraindications
Hypersensitivity or a history of hypersensitivity to the active substance or other components of the drug. Severe hyperthyroidism. Latent hyperthyroidism in doses exceeding 150 mcg of iodine per day. The presence of an autonomous adenoma, as well as focal and diffuse autonomous foci of the thyroid gland at a dose of 300 to 1000 mcg of iodine per day (with the exception of preoperative iodine therapy for the purpose of blocking the thyroid gland according to Plummer). Pulmonary tuberculosis. Hemorrhagic diathesis. Dühring’s dermatitis herpetiformis (Dühring-Brock syndrome).
Recent Reviews