Laferobion nasal spray 100000 IU/ml. 5 ml. vial

Description

Laferobion spray Pharmacological properties

Laferobion spray has an antiproliferative effect on tumor cells, and also has antiviral and immunomodulatory effects. The action of interferon alpha-2b is manifested by its binding to specific receptors on the surface membrane of the cell and initiating a complex of sequential intracellular reactions associated with the induction of a number of enzymes and the implementation of cellular functions, namely: suppression of viral replication in an infected cell and a decrease in the proliferation of tumor cells; with the implementation of immunomodulatory processes (increased phagocytic activity of macrophages, increased specific cytotoxicity of lymphocytes to target cells).

Laferobion spray Indications

The preparation is used in complex therapy in adults and children with:

• acute and chronic viral hepatitis B (moderate and severe forms);
• chronic hepatitis C;
• acute and chronic septic diseases of a viral nature;
• acute viral, bacterial and mixed infections, including in newborns;
• acute and chronic septic diseases of viral and bacterial etiology, including desiminated forms of acute and chroniosepsis;
• herpetic infection of various localization (shingles, multiple skin herpetic eruptions, genital herpes, herpetic keratoconjunctivitis and keratouveitis);
• papillomatosis of the larynx;
• multiple sclerosis;
• malignant melanoma, uveal melanoma, renal cell carcinoma, superficially localized bladder cancer, ovarian and breast cancer, Kaposi’s sarcoma with HIV infection, chronic myeloid leukemia, hairy cell leukemia, non-Hodgkin’s lymphomas, basal cell skin fungus mycosis).

Laferobion spray Application

The preparation is used in the form of a solution. solution of laferobion is administered intravenously (drip), intramuscularly, subcutaneously, intradermally, intraperitoneally, intravesically, rectally, intranasally, subconjunctivally.

Laferobion 100,000 IU for intranasal administration

Laferobion spray Contraindications

Hypersensitivity to the components of the preparation, pregnancy and lactation, thyroid dysfunction, severe visceral disorders in patients with Kaposi’s sarcoma; severe cardiovascular diseases, psoriasis, sarcoidosis, severe liver and / or kidney dysfunction, epilepsy and other diseases of the central nervous system (including functional ones), chronic hepatitis against the background of progressive or decompensated cirrhosis of the liver, chronic hepatitis in patients receiving or recently receiving immunosuppressive therapy (with the exception of a short course of corticosteroid therapy), autoimmune hepatitis, or other autoimmune diseases in history.

Side effects

When using the preparation, it is most often possible to develop a dose-dependent flu-like syndrome (chills, fever, headache, muscle and joint pain, feeling of fatigue).

Possible side effects: impaired thyroid function, impaired vision, liver function, kidney function, electrolyte balance.

With prolonged courses of therapy, leuko- and thrombocytopenia may develop, hypertension and hypotension, vomiting, arthralgia, confusion, dizziness, ataxia, parasthesias, anxiety and depression, hyperexcitability, drowsiness, alopecia, skin rash, pruritus, hot flashes, tachycardia , cough, nosebleeds, herpetic lesions.