Lomflox coated tablets 400 mg. №20

$78.70

This drug is used in the treatment of infections caused by microorganisms sensitive to lomefloxacin. Including:

  • urinary tract infections;
  • respiratory tract infections;
  • ENT infections, including otitis media, sinusitis, tonsillitis;
  • infections of the skin and soft tissues;
  • other infectious diseases;
  • sexually transmitted diseases of gonorrhea, chlamydia, ureaplasmosis, mycoplasmosis;
  • infections of the pelvic organs;
  • tuberculosis.
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Description

Lomflox  composition
active substance: lomefloxacin;
1 tablet contains lomefloxacin hydrochloride equivalent to lomefloxacin 400 mg;
Excipients: anhydrous lactose, corn starch, povidone, sodium starch glycolate (type A), crospovidone, talc, sodium lauryl sulfate, magnesium stearate, propylene glycol, colloidal anhydrous silica, hypromellose, titanium dioxide.

Dosage form
Film-coated tablets.

Pharmacological properties
This drug Lomflox belongs to a group of drugs of the fluoroquinolone group used in the treatment of infections caused by bacteria that can be treated with this drug.
The active component of this drug – lomefloxacin – has the ability to block the bacterial enzyme DNA gyrase.
It has antibacterial activity against bacteria that are resistant to treatment with penicillins, aminoglycosides, cephalosporins, as well as multi-resistant microorganisms.
This drug manifests its therapeutic effect on aerobic gram-negative and gram-positive microorganisms, and also has an anti-tuberculosis effect.
It has an effect on mycobacterium tuberculosis, both external and intracellular, is able to accelerate the resorption of infiltrates.

Indications
This drug Lomflox is used in the treatment of infections caused by microorganisms sensitive to lomefloxacin. Including:

  • urinary tract infections: acute and chronic pyelonephritis, prostatitis, cystitis, epididymitis, surgical urinary tract infections, complicated or recurrent urinary tract infections, infections caused by Pseudomonas aeruginosa and other multi-resistant microorganisms, nosocomial urinary tract infections;
  • respiratory tract infections: pneumonia, pleurisy, empyema, infected bronchiectasis, exacerbations of chronic bronchitis, pulmonary abscesses and cystic fibrosis;
  • ENT infections, including otitis media, sinusitis, tonsillitis;
  • infections of the skin and soft tissues;
  • other infectious diseases: typhoid fever, salmonellosis, shigellosis, infections of the abdominal organs, infections of the biliary tract;
  • sexually transmitted diseases of gonorrhea, chlamydia, ureaplasmosis, mycoplasmosis;
  • infections of the pelvic organs;
  • tuberculosis (as part of complex therapy with basic anti-tuberculosis drugs, as well as with resistance to traditional anti-tuberculosis drugs).

Contraindications
Not applicable if the patient has hypersensitivity (allergy) to one of the components that make up the drug.
Use is contraindicated in:

  • epilepsy;
  • damage to the central nervous system accompanied by convulsions, in particular, after strokes, traumatic brain injuries, inflammatory processes of the central nervous system.

Children
It is not used in pediatrics.

Application during pregnancy and lactation
It is not used to treat pregnant women.
If there is a need to take this drug, then during treatment, lactation (breastfeeding) should be suspended.

Method of administration and dosage
Administered orally, before or after meals. The dose of the drug and the duration of treatment depend on the type, severity of the infection and the effectiveness of the drug, and is prescribed by the attending physician.
The recommended average dosage is 1 tablet (400 mg) once a day, with a duration of treatment of 7-10 days.
In some cases, other dosages are also possible (the exact dosage is determined by the attending physician). In particular, when:

  • prevention of infectious and inflammatory diseases of the urinary tract during transurethral operations – 400 mg once 2-6 hours before the operation;
  • in acute gonorrhea – 600 mg once, chronic gonorrhea – 600 mg per day for 5 days;
  • with urogenital chlamydia, incl. mixed bacterial-chlamydial infection, including gonorrheal-chlamydial infection – 400-600 mg once a day for up to 28 days;
  • chlamydia in patients with rheumatism – 400 mg per day for 20 days;
  • chlamydial conjunctivitis – 400 mg per day, the course of treatment – up to 10 days;
  • mycoplasma – 400-800 mg per day, the course of treatment – up to 10 days;
  • acute, chronic purulent infections of soft tissues, treatment of infected wounds and burns – 400 mg once a day for 5-14 days;
  • chronic osteomyelitis – 400-800 mg per day, the course of treatment is from 3 to 8 weeks;
  • uncomplicated bronchitis and pneumonia – 400 mg once a day for up to 10 days;
  • complicated infections of the lower respiratory tract, including pneumococcal pneumonia, exacerbation of chronic bronchitis – 400-800 mg 1-2 times a day for 14 days;
  • tuberculosis – 400 mg 2 times a day for 14-28 days and longer.

Overdose
In case of an overdose, side effects may occur in the form of:

  • tremor;
  • loss of consciousness;
  • hypersalivation;
  • nausea, vomiting;
  • decreased activity;
  • dyspnea, convulsions.

It is necessary to wash the stomach, take sorbents, establish monitoring of the patient’s condition, and, if necessary, carry out a complex of standard supportive symptomatic therapy.
Hemodialysis and peritoneal dialysis are ineffective.

Side effects
Therapy with this drug can cause side reactions (usually occurring at the end of treatment) in the form of:

  • hot flashes, weakness, back pain, asthenia, facial edema, chills, pain in joints, tendons and muscles (myalgia);
  • abdominal pain, heartburn, dry mouth, thirst, changes in appetite, nausea, vomiting, diarrhea, dyspepsia, flatulence, constipation, stomatitis;
  • pain and ringing in the ears;
  • headache, dizziness, loss of consciousness, sleep disturbances, insomnia, drowsiness, agitation, hallucinations, impaired coordination of movements, depression, thinking disorders, chills, tremors, paresthesias, seizures, ataxia, coma;
  • skin reactions in the form of a rash, allergic urticaria, itching, occasionally – photosensitization reactions, erythema multiforme, hyperemia;
  • purpura, lymphadenopathy, increased fibrinolysis, leukopenia, agranulocytosis, anemia, thrombocytopenia, pancytopenia;
  • hyperglycemia, hypoglycemia, gout;
  • visual impairment, diplopia, conjunctivitis, photophobia, eye pain, lacrimation;
  • vaginal candidiasis, vaginitis, menstrual irregularities, in men – epididymitis, orchitis;
  • liver dysfunction, liver inflammation (hepatitis);
  • disorders of the kidneys, hematuria, dysuric disorders, anuria, polyuria, urinary retention;
  • rhinitis, pharyngitis, dyspnea, cough, nosebleeds, bronchospasms;
  • anaphylactoid reactions;
  • rashes, eczema, acne, skin discoloration, Stevens-Johnson syndrome, skin ulcers, hyperpigmentation;
  • tachycardia, arterial hypertension / hypotension, myocardial infarction, angina pectoris, heart failure, bradycardia, arrhythmia, extrasystole, cyanosis, cardiomyopathy, vasculitis.

Storage conditions and periods
The shelf life of the drug Lomflox is no more than 3 years from the production date indicated on the package.
Store Lomflox in a dry place out of the reach of children, at a temperature not exceeding 25 ° C.