Description

Lomflox Coated Tablets 400 mg. №20

Ingredients:

Lomflox coated tablets contain 400 mg of the active ingredient Lomefloxacin. Other inactive ingredients include microcrystalline cellulose, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol, and FD&C Blue No. 2 Aluminum Lake.

Dosage:

The recommended dosage of Lomflox coated tablets is one 400 mg tablet once daily. It is important to follow the instructions provided by your healthcare provider for the correct dosage and duration of treatment.

Indications:

Lomflox coated tablets are indicated for the treatment of various bacterial infections, including urinary tract infections, respiratory tract infections, skin and soft tissue infections, and sexually transmitted diseases caused by susceptible strains of bacteria.

Contraindications:

Do not take Lomflox tablets if you are allergic to Lomefloxacin or any other ingredients in the product. It is also contraindicated in children, pregnant women, and individuals with a history of tendon disorders related to fluoroquinolone antibiotics.

Directions:

Take Lomflox tablets orally with a full glass of water, with or without food, as directed by your healthcare provider. Do not crush or chew the tablets. Finish the full course of treatment even if you start to feel better, unless otherwise instructed by your doctor.

Scientific Evidence:

Several studies have demonstrated the efficacy of Lomefloxacin in the treatment of various bacterial infections. A study published in the Journal of Antimicrobial Chemotherapy found that Lomefloxacin showed high activity against a wide range of Gram-negative and Gram-positive bacteria, making it a valuable option for empirical therapy.

Pharmacological Effects:

Lomefloxacin, the active ingredient in Lomflox tablets, belongs to the fluoroquinolone class of antibiotics. It works by inhibiting bacterial DNA gyrase, an essential enzyme involved in DNA replication and repair. This mechanism of action leads to the disruption of bacterial DNA synthesis, ultimately killing the bacteria and treating the infection.

Clinical Trials:

In a comparative effectiveness study published in the International Journal of Antimicrobial Agents, Lomefloxacin was found to be as effective as other fluoroquinolones in the treatment of urinary tract infections. The study concluded that Lomefloxacin exhibited similar clinical and microbiological cure rates with a favorable safety profile.

Additional Information:

It is important to note that fluoroquinolone antibiotics, including Lomflox tablets, may cause serious side effects such as tendon rupture, nerve damage, and central nervous system effects. It is crucial to discuss the risks and benefits of treatment with your healthcare provider before starting therapy with Lomflox tablets.