Description

Macrocef Powder for Solution for Injections 1000 mg/1000 mg. №5

Ingredients:

Each vial contains 1000 mg of Ceftriaxone (as Ceftriaxone Sodium) and 1000 mg of Sulbactam (as Sulbactam Sodium).

Dosage:

The recommended dosage is determined by the healthcare provider based on the severity of the infection. It is typically administered intravenously or intramuscularly once or twice a day.

Indications:

Macrocef Powder is indicated for the treatment of various bacterial infections such as respiratory tract infections, skin and soft tissue infections, urinary tract infections, and intra-abdominal infections.

Contraindications:

Do not use Macrocef Powder if you have a known allergy to cephalosporins or beta-lactam antibiotics. It is contraindicated in patients with a history of severe hypersensitivity reactions to any of the components.

Directions:

The powder should be dissolved in the appropriate diluent as directed by the healthcare provider. The reconstituted solution should be used immediately after preparation.

Scientific Evidence:

Ceftriaxone, the active ingredient in Macrocef, is a third-generation cephalosporin with broad-spectrum antibacterial activity. It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. Sulbactam enhances the activity of Ceftriaxone by inhibiting beta-lactamase enzymes produced by some bacteria, thus extending its spectrum of activity.

Studies have shown the efficacy of Ceftriaxone in treating various infections, including those caused by multidrug-resistant bacteria. The combination of Ceftriaxone and Sulbactam in Macrocef provides a synergistic effect, making it a valuable option in the management of serious infections.

Additional Information:

• Macrocef Powder should be stored at controlled room temperature away from moisture and heat.
• It is important to complete the full course of treatment as prescribed, even if symptoms improve before the course is finished.
• Consult a healthcare provider if any adverse reactions or severe side effects occur during treatment.