Description

Maninil (Glibenclamide) Tablets 5 mg

Ingredients

• Active ingredient: Each tablet contains Glibenclamide 5 mg.

Dosage

• Recommended dosage: The usual starting dose is 2.5 to 5 mg daily, taken with breakfast. Adjustments should be based on blood glucose levels.

Indications

• Maninil tablets are used for type 2 diabetes mellitus when diet alone is insufficient for blood sugar control.

Contraindications

• Avoid use in:
• – Type 1 diabetes
• – Diabetic ketoacidosis
• – Severe liver or kidney dysfunction
• – History of sulfonylurea hypersensitivity

Directions

• Take Maninil tablets as directed by your healthcare provider. Swallow whole with water, usually once daily with breakfast.

Scientific Evidence

• Glibenclamide stimulates insulin release from the pancreas, lowering blood sugar levels. Studies support its efficacy in improving glycemic control in type 2 diabetes.

Additional Information

• Regularly monitor blood glucose levels while on Maninil tablets. Inform your healthcare provider of all medications to prevent interactions.

Pharmacological Effects: Glibenclamide, a sulfonylurea, boosts insulin release from beta cells, reducing blood glucose levels.

Clinical Trials: Research shows glibenclamide effectively lowers fasting plasma glucose levels and improves HbA1c in type 2 diabetes patients.