Description
Mefarmil (Metformin Hydrochloride) Coated Tablets 850 mg. №30
Ingredients
- Active ingredient: Metformin hydrochloride 850 mg
Dosage
- Usual starting dose: 500 mg or 850 mg once daily with meals
- Dosage adjustments based on blood glucose levels
Indications
- Adjunct to diet and exercise for glycemic control in adults with type 2 diabetes mellitus
Contraindications
- Avoid in patients with renal impairment, metabolic acidosis, or hypersensitivity to metformin
Directions
- Swallow tablets whole with a full glass of water
- Follow dosage instructions provided
Scientific Evidence
Metformin is a first-line medication for type 2 diabetes, reducing glucose production in the liver and improving insulin sensitivity. Studies show efficacy in lowering blood sugar and reducing complications.
Additional Information
- Formulated for sustained release, providing long-lasting glycemic control
- Monitor blood glucose levels regularly for optimal efficacy and safety
Pharmacological Effects: Increases glucose uptake, decreases absorption, affects lipid metabolism, may aid weight loss.
Clinical Trials: Metformin improves glycemic control and reduces cardiovascular event risk. A study in the New England Journal of Medicine showed reduced incidence of major cardiovascular events compared to placebo.
