Methyluracil (methyluracilum) rectal suppositories 0.5 g. №10

Description

Methyluracil composition
active substance: methyluracilum;
1 suppository contains methyluracil – 500 mg;
excipient: solid fat.

Dosage form
Rectal suppositories.

Pharmacological properties
This pharmaceutical preparation Methyluracil belongs to the group of non-steroidal anti-inflammatory drugs.
The main active ingredient is methyluracil, a pyramidine derivative.
In particular, methyluracil is able to accelerate cell regeneration, stimulate the protection of cells and tissues, produces an anti-inflammatory effect, and also has an immunostimulating effect.
Able to stimulate the synthesis of nucleic acids (high molecular weight organic compound – biopolymer), normalizing their metabolism.
As a result, the regeneration processes are accelerated. This also applies to rapidly proliferating cells of the mucous membranes of the digestive tract, stomach, duodenum 12.
It has an erythropoietic and leukopoietic effect, produces a moderate anti-inflammatory effect. It has a positive effect on the immune system, incl. its humoral and cellular components.

Indications
This drug Methyluracil is used in the treatment of various inflammatory, erosive and ulcerative diseases in the lower part of the large intestine, which can be treated with methyluracil.
In particular, this drug is used to treat:

• erosive and ulcerative colitis;
• proctitis;
• sigmoiditis;
• cracks in the anus.

Contraindications
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components.
Also contraindicated for:

• acute and chronic forms of leukemia;
• lymphogranulomatosis (Hodgkin’s disease, malignant granuloma);
• malignant diseases of the bone marrow.

Children
Not used in pediatric practice until the age of 14.

Application during pregnancy and lactation
This drug should not be used in the treatment of pregnant women, since there is no clinical experience and it is not known how dangerous its use is, both for the woman and the fetus.
If it is necessary to take the drug during breastfeeding, it is advisable to interrupt lactation.

Method of administration and dosage
Methyluracil is used as a rectal suppository. It should be removed from the blister and inserted into the rectum after bowel movement.
Adults and children over the age of 14 can use this drug 1 to 4 times a day.
The duration of treatment ranges from 7 days to 4 months and is determined by the attending physician on an individual basis, depending on the nature of the disease, the effect of the drug on the body and the patient’s recovery rate

Overdose
Overdose can cause increased side effects.
In case of an accidental overdose, its use should be discontinued, as well as the stomach should be rinsed, a saline laxative, enterosorbents should be taken.

Side effects
The drug is usually well tolerated. In some cases, hypersensitivity reactions are possible, such as:

• headache;
• dizziness;
• heartburn, allergic reactions, allergic urticaria, itching;
• after the introduction of the suppository in the rectum, a burning sensation, an itching sensation may be felt for some time.

If side effects appear, the use of the drug should be suspended or the dose used should be reduced.

Storage conditions and periods
Expiration date – up to 3 years from the production date indicated on the package.
Storage temperature should not exceed 25 ° C.