Description
Miraxol (pramipexole) Tablets 0.25 mg. №30
Ingredients
- Active ingredient: Pramipexole 0.25 mg per tablet.
Dosage
- Dosage: The recommended starting dose is 0.125 mg three times daily, adjusted based on individual response.
Indications
- Indications: Miraxol tablets are used for Parkinson’s disease and restless legs syndrome (RLS).
Contraindications
- Contraindications: Avoid if allergic to pramipexole or any tablet components. Caution with kidney problems.
Directions
- Directions: Swallow tablets whole with water as directed. Do not crush or chew.
Scientific Evidence
Pramipexole, the active ingredient, acts as a dopamine agonist, enhancing motor symptoms in Parkinson’s disease and alleviating RLS symptoms.
Additional Information
- Miraxol tablets should be stored at room temperature, away from moisture and heat. Keep out of children’s reach.
- Seek immediate medical help for severe side effects or allergic reactions.
Pharmacological Effects
- Pramipexole stimulates dopamine D2 and D3 receptors, improving motor function in Parkinson’s disease and modulating dopamine levels in the brain.
- It regulates dopamine activity, crucial for movement control, and eases RLS symptoms by affecting dopamine in the central nervous system.
Clinical Trials and Comparative Effectiveness
- Clinical trials support pramipexole’s efficacy in managing Parkinson’s disease and RLS symptoms.
- Compared to other dopamine agonists, pramipexole shows similar effectiveness and favorable side effect profiles, with potential for better tolerability and sustained efficacy in long-term treatment.
