Description
Motorix (Domperidone) Coated Tablets 0.01 g. №30
Ingredients
- Active ingredient: Domperidone 0.01 g per tablet.
Dosage
- Recommended dosage: The usual dose is 1-2 tablets taken 3-4 times a day before meals. Do not exceed the maximum daily dose of 8 tablets.
Indications
- Motorix tablets are indicated for the relief of symptoms of nausea and vomiting.
Contraindications
- Do not use Motorix tablets if you have a known hypersensitivity to domperidone or any of the excipients.
Directions
- Swallow the tablets whole with a glass of water. Do not crush or chew the tablets. Take as directed by your healthcare provider.
Scientific Evidence
- Domperidone, the active ingredient in Motorix tablets, exerts its antiemetic effect by blocking dopamine receptors in the chemoreceptor trigger zone of the brain.
- Studies have shown that domperidone is effective in the treatment of nausea and vomiting, particularly in conditions such as gastroenteritis and chemotherapy-induced nausea.
Additional Information
- Motorix tablets have been widely used in clinical practice for the management of gastrointestinal motility disorders.
- It is important to follow the recommended dosage and not exceed the maximum daily dose to avoid potential side effects.
- If symptoms persist, consult a healthcare professional for further evaluation.
Pharmacological Effects: Domperidone acts as a dopamine antagonist, resulting in increased gastrointestinal motility and decreased nausea and vomiting. It has a low propensity to cross the blood-brain barrier, reducing the risk of central side effects.
Clinical Trials: Clinical trials have shown the efficacy of domperidone in treating nausea and vomiting. For instance, a study by Khanna et al. (2018) demonstrated that domperidone was more effective than placebo in reducing the frequency and severity of nausea in patients with functional dyspepsia.
