Mycamine powder for solution for infusions 100 mg. №1 vial

Description

Mycamine composition
active substance: micafungin;
1 vial contains 100 mg of micafungin (as micafungin sodium);
Excipients: lactose monohydrate, citric anhydrous acid, sodium hydroxide.

Dosage form
Powder for solution for infusion.

Pharmacological properties
This Mycamine pharmaceutical product belongs to the polyene group antibiotics used as an antifungal agent.
The main active ingredient is mycofungin, an echinocandin derivative. Has the ability to inhibit the synthesis of one of the most important components of the walls of yeast-type fungi “candida”. It also treats esophageal candidiasis, and can also be used as a prophylactic agent to prevent yeast lesions in some invasive procedures.
When it enters the body, it spreads through all its tissues and organs, binding by 99% to plasma proteins. It is excreted mainly with feces.

Indications
The specified pharmaceutical product Mycamine is used to treat certain types of mycoses. In particular, it is effective in patients suffering from esophageal candidiasis.
It can also be used as a prophylactic agent to prevent the development of candidiasis in patients after hematopoietic stem cell transplantation.

Contraindications
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.

Application during pregnancy and lactation
Use during pregnancy is possible only if the intended benefit to the mother outweighs the potential risk to the fetus and only in established cases of extreme necessity. Application during lactation is possible only in cases where the intended benefit to the mother outweighs the potential risk to the infant.
If there is a need to take the drug during lactation, then it should be suspended for the period of treatment.

Method of administration and dosage
This Mycamine drug is used by injection, intravenously (in the form of infusion), once a day.
The recommended daily dosage is 150 mg of micafungin per day.
Introduction – slow, for at least 60 minutes.
For the prevention of candidiasis in patients after hematopoietic stem cell transplantation, the recommended dose is 50 mg per day.
The duration of use is set individually.
The duration of treatment, a more accurate dosage and its correction are determined individually by the attending physician.

Overdose
Overdose can cause increased side effects.
In case of excessive ingestion, it is recommended to apply symptomatic treatment, to make a blood transfusion.

Side effects
When treating with this drug, side effects are possible such as:

• nausea, vomiting, abdominal pain, diarrhea, loss of appetite, hyperbilirubinemia, constipation, dyspepsia;
• anemia, neutropenia, eosinophilia, thrombocytopenia, leukopenia, lymphopenia;
• cough, bronchospasm, rash, allergic urticaria, facial flushing, fever, drowsiness, delirium, headache, dizziness;
• hypokalemia, hypophosphatemia, hypomagnesemia.

Storage conditions and periods
Expiration date – no more than 2 years from the date of issue indicated on the packaging by the manufacturer.
Storage temperature should not exceed 25 ° C.