$19.20
Topical treatment of pathological conditions of the musculoskeletal system, characterized by pain, inflammation and stiffness of movements, such as osteoarthritis, periarthritis, post-traumatic tendinitis, tendosynovitis, muscle strain, heavy physical exertion on the joints.
Description
Nimid composition
active substance: nimesulide;
1 g of gel contains 10 mg of nimesulide;
Excipients: benzyl alcohol, propylene glycol, carbomer 940, disodium edetate, sodium hydroxide, flavor Cologne Comp 530, purified water.
Dosage form
Gel for external use.
Packed in 100 g in a tube.
Pharmacological properties
Nimesulide is a non-steroidal anti-inflammatory drug (NSAID), a selective cyclooxygenase-2 inhibitor. In terms of anti-inflammatory activity, nimesulide in equimolar concentration in the initial stage of inflammation is equated to indomethacin and piroxicam. By inhibiting the synthesis of prostaglandins in the area of inflammation, nimesulide has virtually no effect on the synthesis of regulatory prostaglandins in the stomach wall and kidneys. Inhibits the activity of platelet activating factor, α-tumor necrosis factor, proteinases, histamine and the formation of free oxygen radicals. When applied topically, it reduces or disappears pain at the application site, including joint pain, reduces morning stiffness and swelling of the joints.
Indication
Topical treatment of pathological conditions of the musculoskeletal system, characterized by pain, inflammation and stiffness of movements, such as osteoarthritis, periarthritis, post-traumatic tendinitis, tendosynovitis, muscle strain, heavy physical exertion on the joints.
Contraindication
Hypersensitivity to nimesulide or to other components of the drug.
Dermatitis and infectious skin diseases. Damage to the epidermis. Do not use in patients in whom acetylsalicylic acid or other drugs that inhibit prostaglandin synthesis cause allergic reactions such as rhinitis, urticaria or bronchospasm.
Children
Do not apply to children.
Use during pregnancy or breastfeeding
Do not use during pregnancy or breastfeeding.
Method of application and dosage
Apply Nimid externally to adults. The skin surface should be washed and dried before applying the gel. Apply a strip of gel about 3 cm long on painful areas of the body in a thin layer and rub lightly, the frequency of application is 3-4 times a day.
The duration of Nimid therapy is determined individually depending on the effectiveness of therapy and is not more than 4 weeks.
Overdose
If the gel is applied to large areas of skin or in excess of the recommended doses, systemic side effects characteristic of nimesulide and other nonsteroidal anti-inflammatory drugs are possible: dyspepsia, headache, dizziness, epigastric pain.
Treatment: dose reduction or discontinuation of the drug. Therapy is symptomatic.
Side effects:
- From the skin: local skin irritation of mild to moderate erythema, rash, peeling, itching, allergic reactions.
- From the immune system: hypersensitivity reactions, including anaphylactic reactions such as Quincke’s edema, vasomotor rhinitis, dyspnea and bronchospasm.
Expiration date
3 years.
Storage conditions
Store Nimid at a temperature not exceeding 25 ° C in the original package.
Do not freeze.
Keep out of reach of children.
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