$16.00
The drug is indicated for the treatment and prevention of ischemic neurological disorders, which are caused by spasm of the cerebral vessels that have arisen after subarachnoid hemorrhage as a result of ruptured aneurysm. Also, this drug is indicated for the treatment of functional disorders of brain activity in elderly people with severe symptoms (impaired concentration, memory loss, mood changes).
Description
Nimodipin composition and form of release
The active component of this pharmaceutical is nimodipine. The tool is available in tablets.
Pharmacological properties
Nimodipin has an antispasmodic, vasodilating effect on the smooth muscle of the cerebral vessels. This medicine prevents the occurrence and eliminates vascular spasms, which are caused by the vasoconstrictor effect of prostaglandins, serotonin, histamine.
The drug increases perfusion (blood flow) in the affected areas of the brain that are caused by impaired blood supply, especially after subarachnoid hemorrhage.
Nimodipin stabilizes the functional state of neurons. The therapeutic effect of this drug is manifested in a decrease in the severity of neurological symptoms caused by ischemia (oxygen deficiency) of the brain.
Indications
The drug is indicated for the treatment and prevention of ischemic neurological disorders, which are caused by spasm of the cerebral vessels that have arisen after subarachnoid hemorrhage as a result of ruptured aneurysm. Also, this drug is indicated for the treatment of functional disorders of brain activity in elderly people with severe symptoms (impaired concentration, memory loss, mood changes).
Contraindications
It is forbidden to use the drug in case of hypersensitivity to it, severe liver failure, an attack of unstable angina pectoris, children under eighteen years of age, in the acute period of myocardial infarction, as well as for a month after it.
It is also forbidden to use this drug in combination with antiepileptic drugs (phenobarbital, carbamazepine, phenytoin), rifampicin, as this leads to a significant decrease in the effectiveness of nimodipine.
Application during pregnancy and lactation
During pregnancy, the drug is used in exceptional cases; the need for its use is established by the attending doctor.
If it is necessary to use Nimodipin in women who are breastfeeding, it is necessary to stop feeding during the period of therapy.
Method of administration and dosage
The tablets are taken orally one hour before or two hours after a meal.
After subarachnoid hemorrhage, it is recommended to receive the drug in a dose of 60 mg (2 tablets) six times a day; the break between doses should be at least four hours. At this dosage, the drug should be taken within seven days, and then the dose must be reduced. The duration of Nimodipin treatment is 21 days.
In case of functional disorders of brain activity in the elderly, Nimodipine is used one tablet (30 mg) three times a day. The duration of the course of drug therapy is set individually (it can last for several months).
Overdose
In case of an acute overdose of the drug, severe arterial hypotension (pressure drop), nausea, bradycardia or tachycardia, disruption of the digestive tract, signs of disruption of the central nervous system occur.
Side effects
When using the drug, the following side effects may occur: a marked decrease in blood pressure (rarely – an increase), diarrhea, gastrointestinal bleeding, nausea, jaundice, vomiting, hepatitis, hot flashes (facial flushing, a feeling of heat), tachycardia (less often – bradycardia), increased sweating, weakness, rebound vasospasm, headache, shortness of breath, deep venous thrombosis, dizziness, sleep disorders, edema, itching, aggressiveness, depression, skin rashes.
Storage conditions and periods
The shelf life of the tablets is five years.
It is necessary to store at temperatures below + 25 ° С out of the reach of children.
Recent Reviews