Description

Nistatin (Nistatinum) Coated Tablets 500000 IU №20

Ingredients:

Each coated tablet contains 500,000 IU of Nistatin (Nistatinum) as the active ingredient.

Dosage:

The usual dosage is 1 tablet to be taken orally 3 times a day. Consult a healthcare professional for personalized dosing instructions.

Indications:

Nistatin coated tablets are indicated for the treatment of fungal infections caused by Candida species. These infections can affect various parts of the body, including the mouth, throat, and intestines.

Contraindications:

Do not use Nistatin tablets if you are allergic to Nistatin or any other antifungal medications. Pregnant or breastfeeding women should consult their doctor before using this medication.

Directions:

Swallow the tablets whole with a full glass of water. Do not crush or chew the tablets. It is important to complete the full course of treatment as prescribed by your healthcare provider.

Scientific Evidence:

Nistatin is a well-established antifungal medication that has been used for decades to treat various fungal infections. Studies have shown its efficacy in combating Candida infections, with minimal side effects. Research published in the Journal of Antimicrobial Chemotherapy highlighted the effectiveness of Nistatin in treating oral thrush, a common Candida infection in the mouth.

Additional Information:

Nistatin works by disrupting the cell membrane of the fungi, leading to their death. It is considered a fungicidal agent, meaning it kills the fungi rather than just inhibiting their growth. Compared to other antifungal medications, Nistatin is known for its low absorption into the bloodstream, reducing the risk of systemic side effects. Consult your healthcare provider for more information on the use of Nistatin tablets.

Pharmacological effects of Nistatin involve its ability to bind to sterols in the fungal cell membrane, disrupting the membrane integrity and leading to cell death. This mechanism of action makes it an effective treatment for Candida infections while minimizing the development of resistance.

Clinical trials have shown Nistatin to be as effective as other antifungal agents in treating Candida infections, with a good safety profile. Its use in both adults and pediatric populations further demonstrates its versatility and efficacy in managing fungal infections.