Description
No-shpa Solution for Injections Ampoules 20 mg/ml. 2 ml. №5
Ingredients:
- Each 2 ml ampoule contains 20 mg of Drotaverine Hydrochloride.
Dosage:
- The usual dose is 40-80 mg per day, divided into 2-3 administrations.
- Dosage may vary based on individual patient needs and medical condition.
Indications:
- No-shpa Solution for Injections is indicated for the treatment of smooth muscle spasms.
- Commonly used to relieve pain and discomfort associated with conditions such as renal colic, biliary colic, and dysmenorrhea.
Contraindications:
- Do not use No-shpa Solution for Injections in cases of hypersensitivity to Drotaverine or other ingredients in the formulation.
- Contraindicated in patients with severe hepatic or renal impairment.
Directions:
- Administer No-shpa Solution for Injections via intramuscular or slow intravenous injection.
- The injection should be given slowly to minimize the risk of adverse effects.
Scientific Evidence:
No-shpa (Drotaverine) acts by inhibiting phosphodiesterase enzyme and calcium influx, leading to smooth muscle relaxation. Studies have shown its efficacy in relieving smooth muscle spasms with a favorable safety profile.
Additional Information:
- Drotaverine has comparable effectiveness to other antispasmodic agents like Mebeverine and Hyoscine butylbromide.
- Rapid onset of action and minimal side effects make it a preferred choice in acute spasmodic pain management.
- Its mechanism of action involves direct relaxation of smooth muscles without affecting normal gut motility, suitable for conditions like irritable bowel syndrome and colicky pain.
