Description

Onglyza (saxagliptin) Coated Tablets 2.5 mg. №30

Ingredients

Active ingredient: Saxagliptin 2.5 mg.
Other ingredients: Lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, and magnesium stearate.

Dosage

Recommended dosage: The usual dose is one 2.5 mg tablet once daily, with or without food.

Indications

Onglyza (saxagliptin) tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Contraindications

Do not use Onglyza if:

• You have a history of a serious hypersensitivity reaction to saxagliptin.
• You have type 1 diabetes mellitus or diabetic ketoacidosis.

Directions

Take Onglyza exactly as prescribed by your healthcare provider. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Scientific Evidence

Onglyza (saxagliptin) has been extensively studied in clinical trials. Research has shown that saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, effectively lowers blood sugar levels by increasing insulin release and decreasing glucagon secretion. Studies have demonstrated its efficacy in improving glycemic control in patients with type 2 diabetes.

Additional Information

It is important to monitor your blood sugar levels regularly while taking Onglyza. Inform your healthcare provider about any side effects or concerns. This medication should be used in conjunction with a healthy diet and regular exercise routine.

Pharmacologically, saxagliptin works by inhibiting the enzyme DPP-4, which in turn increases the levels of incretin hormones. These hormones stimulate insulin release and inhibit glucagon secretion, leading to improved blood glucose control.

Comparative studies have shown that saxagliptin, the active ingredient in Onglyza, has similar efficacy to other DPP-4 inhibitors in managing blood sugar levels in patients with type 2 diabetes. However, individual responses to different medications may vary, and it is essential to work closely with your healthcare provider to find the most suitable treatment.