Description

Oxitocin (Oxytocin) Solution for Injections 5 IU 1ml Ampoules №10

Ingredients:

Each 1ml ampoule contains 5 IU of Oxytocin as the active ingredient. Other ingredients may include sodium chloride, acetic acid, and water for injection.

Dosage:

The usual dose is 5-10 IU administered by intramuscular or intravenous injection. Dosage may vary based on the specific indication and patient response.

Indications:

Oxytocin is indicated for the induction of labor, augmentation of labor, and prevention and treatment of postpartum hemorrhage. It may also be used in the management of incomplete or inevitable abortion.

Contraindications:

Do not use Oxytocin in cases of fetal distress, prematurity, or hypersensitivity to the drug. It should be used with caution in patients with hypertensive disorders.

Directions:

Administer Oxytocin under the supervision of a healthcare provider experienced in its use. Follow the recommended dosage and administration guidelines closely.

Scientific Evidence:

Oxytocin, a hormone produced in the hypothalamus, plays a crucial role in uterine contractions during labor and milk ejection during breastfeeding. Studies have shown that Oxytocin administration effectively stimulates uterine contractions, reducing the risk of postpartum hemorrhage and aiding in labor progression.

Additional Information:

Oxytocin is a well-established medication in obstetric practice due to its oxytocic properties. It is considered a safe and effective intervention when used appropriately under medical supervision. Research supports its role in improving maternal outcomes during childbirth.

Pharmacological Effects: Oxytocin acts by binding to oxytocin receptors on the uterine smooth muscle, leading to increased intracellular calcium levels and uterine contractions. It also has vasodilatory effects, contributing to its role in preventing postpartum hemorrhage.

Clinical Trials: Clinical trials have demonstrated the efficacy of Oxytocin in reducing the duration of labor, decreasing the need for cesarean sections, and lowering the risk of excessive bleeding after childbirth. Comparative studies have shown Oxytocin to be superior to other uterotonic agents in certain clinical scenarios.