Description

Pentasa (mesalazine) granules 2 g. sackets №60

Ingredients

Active ingredient: Mesalazine.
Other ingredients: Sucrose, maize starch, talc, ethylcellulose, diethylphthalate, colloidal anhydrous silica, and povidone.

Dosage

Adults: The usual dose is 2-4 g daily, divided into 2-4 doses.
Children: Dosage should be determined by a healthcare provider.

Indications

Pentasa granules are indicated for the treatment of mild to moderate ulcerative colitis and maintenance of remission.

Contraindications

Do not use Pentasa if you are allergic to mesalazine or any of the ingredients. Consult a doctor before use if you have kidney or liver problems.

Directions

Mix the granules with water or fruit juice before taking. Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Studies have shown that mesalazine, the active ingredient in Pentasa, is effective in inducing and maintaining remission in ulcerative colitis. Research published in the “Journal of Gastroenterology” demonstrated the efficacy of mesalazine in reducing inflammation in the colon.

Additional Information

Pentasa granules work by reducing inflammation in the colon, thereby alleviating symptoms of ulcerative colitis. Clinical trials have shown that mesalazine is well-tolerated and has a good safety profile compared to other medications used for the same indication.

Pharmacological Effects: Mesalazine exerts its anti-inflammatory effects by inhibiting the production of inflammatory mediators in the colon. It also scavenges free radicals, further reducing inflammation.

Clinical Trials: In a comparative study published in the “American Journal of Gastroenterology,” Pentasa was found to be as effective as sulfasalazine in maintaining remission in ulcerative colitis patients, with fewer side effects.