Description

Pimafucin (Natamycin) Vaginal Suppositories 100 mg. №3

Ingredients

Active ingredient: Natamycin 100 mg.
Other ingredients: Hard fat.

Dosage

Recommended dosage: Insert one suppository into the vagina once daily, preferably at bedtime, for 3 consecutive days.

Indications

Pimafucin vaginal suppositories are indicated for the treatment of vaginal yeast infections (vaginal candidiasis).

Contraindications

Do not use Pimafucin vaginal suppositories if you are allergic to natamycin or any other ingredients in the product.

Directions

– Wash your hands before and after using the suppository.
– Lie on your back with your knees bent, then gently insert the suppository into the vagina as far as possible using your finger.
– Wash your hands after application.

Scientific Evidence

Natamycin, the active ingredient in Pimafucin, is a polyene antifungal agent that works by binding to ergosterol in the fungal cell membrane, disrupting membrane integrity and leading to cell death. Studies have shown natamycin to be effective against various fungal infections, including vaginal candidiasis. Research published in the Journal of Antimicrobial Chemotherapy demonstrated the efficacy of natamycin in treating vaginal yeast infections with minimal side effects.

Additional Information

Pimafucin vaginal suppositories offer a targeted approach to treating vaginal yeast infections, providing localized therapy directly to the site of infection. This can result in faster symptom relief compared to oral antifungal medications. It is important to complete the full course of treatment as prescribed to ensure the infection is fully eradicated and to prevent recurrence.

Pharmacological Effects and Clinical Trials

Natamycin exhibits potent antifungal activity by disrupting the fungal cell membrane, making it an effective treatment for various fungal infections. Clinical trials have demonstrated the efficacy of natamycin in treating vaginal candidiasis, with high cure rates and low recurrence rates. Additionally, the localized administration of natamycin via vaginal suppositories minimizes systemic exposure, reducing the risk of systemic side effects commonly associated with oral antifungal agents.

Overall, Pimafucin (natamycin) vaginal suppositories 100 mg. №3 offer a safe and effective treatment option for vaginal yeast infections, supported by scientific evidence and clinical trials showcasing its efficacy and tolerability.