Description

Portalak (lactulose) syrup 667 mg/ml. 250 ml. №1 vial

Ingredients

Active ingredient: Lactulose 667 mg/ml.

Dosage

Dosage: The usual adult dose is 15-30 ml daily, adjusted according to individual response.

Indications

Indications: Portalak syrup is indicated for the treatment of constipation and hepatic encephalopathy.

Contraindications

Contraindications: Do not use Portalak syrup if you are allergic to lactulose or if you have galactosemia.

Directions

Directions: Take Portalak syrup orally, with or without food. Shake the bottle well before each use.

Scientific Evidence

Lactulose, the active ingredient in Portalak syrup, works by drawing water into the colon, softening the stool and increasing bowel movements. This mechanism helps relieve constipation and reduce ammonia levels in hepatic encephalopathy. Studies have shown that lactulose is effective in improving constipation and managing hepatic encephalopathy symptoms.

Additional Information

Portalak syrup is well-tolerated, with minimal side effects such as bloating or gas. It is important to drink plenty of water while using this medication to prevent dehydration. Consult your healthcare provider for proper dosage and duration of treatment.

Pharmacological Effects: Lactulose is a synthetic disaccharide that is not absorbed in the small intestine but is fermented by gut bacteria in the colon. This fermentation process leads to the production of short-chain fatty acids and lactic acid, which acidify the colonic contents, promoting the growth of beneficial bacteria and softening the stool.

Clinical Trials: Clinical trials have demonstrated the efficacy of lactulose in the management of chronic constipation and hepatic encephalopathy. A study published in the Journal of Gastroenterology and Hepatology showed that lactulose significantly improved stool frequency and consistency in patients with chronic constipation.