$98.00
Purpose: Dinoprostone gel induces cervical ripening for labor induction.
Description
Prepidil (dinoprostone) gel 0.5 mg/3g. syringe 3g. №1
Ingredients
Active ingredient: Dinoprostone. Inactive ingredients: Carbomer 974P, dinatrium edetate, hydroxypropyl cellulose, propylene glycol, purified water.
Dosage
Dosage: The recommended dose is 0.5 mg (1/3 of the syringe) administered intracervically. The total dose should not exceed 1.5 mg in a 24-hour period.
Indications
Indicated for: Induction of labor in pregnant women at or near term with a medical or obstetrical need for the induction of labor.
Contraindications
Contraindications: Hypersensitivity to prostaglandins, acute pelvic inflammatory disease, unexplained vaginal bleeding during this pregnancy, and others as outlined in the prescribing information.
Directions
Administration: Prepidil should be administered by a healthcare provider trained in obstetrical care. The gel should be inserted into the endocervical canal using a syringe provided with the product.
Scientific Evidence
Pharmacological Effects: Dinoprostone, the active ingredient in Prepidil, is a prostaglandin E2 analogue that acts locally on the cervix, causing softening, effacement, and dilation, leading to the initiation of labor.
Clinical Trials: Clinical studies have demonstrated the efficacy of dinoprostone gel in inducing labor in women with various indications. A study by Wing et al. (2018) showed a significant reduction in the time to delivery with dinoprostone gel compared to placebo.
Additional Information
Prepidil is a well-established medication used in obstetrics for the induction of labor. It is considered safe and effective when administered by trained healthcare professionals following the recommended dosage guidelines.
Patients should be closely monitored during and after administration of Prepidil for any signs of hypersensitivity reactions or uterine hyperstimulation. In case of adverse events, appropriate interventions should be promptly initiated.
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