Description

Prostin E2 (dinoprostone) gel vaginal 1 mg/3g. 3g. syringe №1

Ingredients:

Each 3g syringe contains 1 mg of dinoprostone.

Dosage:

The usual dose is 1 dose (3g) administered vaginally.

Indications:

Prostin E2 gel is indicated for the termination of pregnancy, treatment of nonmalignant hypertonic uterine dysfunction, and for cervical ripening.

Contraindications:

Do not use Prostin E2 in cases of known hypersensitivity to prostaglandins, acute pelvic inflammatory disease, active cardiac, pulmonary, renal, or hepatic disease.

Directions:

Administer the gel deep into the vagina. Dosage and duration should be individualized based on the specific indication.

Scientific Evidence:

Dinoprostone, the active ingredient in Prostin E2, is a synthetic prostaglandin E2 analog that acts locally on the uterus to induce contractions. Studies have shown that dinoprostone is effective in cervical ripening and inducing labor in pregnant women. Research published in the American Journal of Obstetrics and Gynecology demonstrated the efficacy of dinoprostone gel in achieving successful vaginal delivery within 12 hours of administration in women with unfavorable cervices.

Additional Information:

Prostin E2 gel should be used with caution in patients with a history of asthma, glaucoma, or epilepsy. It may cause uterine hyperstimulation, which can lead to fetal distress. Close monitoring during use is essential. Consult a healthcare provider for personalized recommendations.

Overall, Prostin E2 gel is a well-established medication for various obstetric and gynecological conditions. Its efficacy and safety profile make it a valuable option in managing pregnancy-related issues. Always follow the prescribed dosage and recommendations for optimal outcomes.