Description

Proxium powder for solution for infusion 40 mg. №1 vial

Ingredients

Proxium powder for solution for infusion 40 mg contains the active ingredient esomeprazole. Other ingredients may include mannitol, crospovidone, citric acid, sodium hydroxide, and hydrochloric acid.

Dosage

The recommended dosage of Proxium powder for solution for infusion is 40 mg once daily. The powder should be reconstituted with sterile water for injection and administered intravenously over 10-30 minutes.

Indications

Proxium powder for solution for infusion is indicated for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, and gastric ulcers caused by Helicobacter pylori infection.

Contraindications

Do not use Proxium powder for solution for infusion if you are allergic to esomeprazole or any other ingredients in the product. It is also contraindicated in patients taking medications such as nelfinavir or atazanavir.

Directions

Follow the instructions provided by your healthcare provider for the proper reconstitution and administration of Proxium powder for solution for infusion. Do not mix the powder with other medications or solutions.

Scientific Evidence

Studies have shown that esomeprazole, the active ingredient in Proxium, is effective in reducing gastric acid secretion and healing of erosive esophagitis. Research published in the American Journal of Gastroenterology demonstrated the superior efficacy of esomeprazole compared to other proton pump inhibitors in the treatment of GERD.

Additional Information

It is important to note that Proxium powder for solution for infusion should be used under the supervision of a healthcare professional. Inform your doctor about any other medications you are taking to avoid potential drug interactions.

Proxium exerts its pharmacological effects by irreversibly inhibiting the proton pump in gastric parietal cells, thereby reducing acid secretion. This action helps in the treatment of acid-related disorders such as GERD and ulcers.

Clinical trials have shown that Proxium is well-tolerated and effective in providing symptom relief and healing of esophageal lesions. Patients treated with Proxium have reported significant improvement in quality of life and reduction in reflux symptoms.