Description

Refordez-Novofarm (hydroxyethyl starch) solution for infusions 6% 200 ml. vial

Ingredients

Active ingredient: Hydroxyethyl starch
Inactive ingredients: Water for injection

Dosage

The dosage of Refordez-Novofarm solution should be individualized based on the patient’s condition, weight, and medical history. It is typically administered intravenously over a specific period as directed by a healthcare professional.

Indications

Refordez-Novofarm solution is indicated for the treatment of hypovolemia (low blood volume) and shock. It helps to restore and maintain adequate blood volume to support vital organ functions.

Contraindications

Do not use Refordez-Novofarm solution in patients with known hypersensitivity to hydroxyethyl starch or in cases of severe renal impairment. It is important to assess the patient’s medical history and current condition before administration.

Directions

Refordez-Novofarm solution is for intravenous use only. It should be administered by a healthcare provider in a controlled clinical setting. The rate of infusion and total volume to be administered should be carefully monitored.

Scientific Evidence

Studies have shown that hydroxyethyl starch solutions like Refordez-Novofarm can effectively expand plasma volume and improve hemodynamic stability in patients with hypovolemia and shock. Research published in the Journal of Intensive Care supports the use of hydroxyethyl starch solutions for fluid resuscitation in critically ill patients.

Additional Information

It is essential to monitor patients receiving Refordez-Novofarm solution for signs of fluid overload, coagulopathy, and renal function. Close medical supervision is necessary to ensure the safe and effective use of this medication.

Pharmacologically, hydroxyethyl starch works by expanding plasma volume, which leads to an increase in cardiac output and tissue perfusion. This mechanism helps improve blood pressure and organ perfusion in patients with hypovolemia.

Clinical trials have demonstrated the comparative effectiveness of hydroxyethyl starch solutions in rapidly restoring intravascular volume compared to crystalloid solutions. However, the choice of fluid therapy should be based on the individual patient’s condition and needs.