Description
Refordez-Novofarm (Hydroxyethyl Starch) Solution for Infusions 6% 400 ml Vial
Ingredients
- Active Ingredient: Hydroxyethyl Starch
Dosage
- Dosage: The dosage of Refordez-Novofarm solution for infusions should be determined by a healthcare professional based on the patient’s condition and needs.
Indications
- Indications: Refordez-Novofarm is indicated for the treatment of hypovolemia (low blood volume) and hypotension (low blood pressure) in various clinical settings.
Contraindications
- Contraindications: Refordez-Novofarm is contraindicated in patients with known hypersensitivity to hydroxyethyl starch, in patients with severe renal impairment, and in patients with intracranial bleeding.
Directions
- Directions: Refordez-Novofarm solution is for intravenous use only. It should be administered by a healthcare professional following the recommended dosage guidelines.
Scientific Evidence
- Refordez-Novofarm (Hydroxyethyl Starch) Solution: Studies have shown that hydroxyethyl starch solutions can effectively expand plasma volume and improve hemodynamic parameters in critically ill patients. In a study published in the Journal of Intensive Care, hydroxyethyl starch solutions were associated with a significant increase in mean arterial pressure and cardiac index compared to crystalloid solutions in patients with septic shock.
Additional Information
- It is important to monitor patients receiving Refordez-Novofarm for signs of fluid overload, renal impairment, and coagulopathy. The use of hydroxyethyl starch solutions has been associated with adverse effects such as renal dysfunction and coagulopathy, especially in patients with pre-existing renal impairment. Healthcare providers should assess the patient’s fluid status, renal function, and overall clinical condition before initiating treatment with hydroxyethyl starch solution.