Description

Refordez-Novofarm (hydroxyethyl starch) solution for infusions 6% 400 ml. vial

Ingredients

Active ingredient: Hydroxyethyl starch

Dosage

Dosage: The dosage of Refordez-Novofarm solution for infusions should be determined by a healthcare professional based on the patient’s condition and needs.

Indications

Indications: Refordez-Novofarm is indicated for the treatment of hypovolemia (low blood volume) and hypotension (low blood pressure) in various clinical settings.

Contraindications

Contraindications: Refordez-Novofarm is contraindicated in patients with known hypersensitivity to hydroxyethyl starch, in patients with severe renal impairment, and in patients with intracranial bleeding.

Directions

Directions: Refordez-Novofarm solution is for intravenous use only. It should be administered by a healthcare professional following the recommended dosage guidelines.

Scientific Evidence

Refordez-Novofarm (hydroxyethyl starch) solution has been studied in various clinical trials to evaluate its efficacy and safety in the management of hypovolemia and hypotension. Research has shown that hydroxyethyl starch solutions can effectively expand plasma volume and improve hemodynamic parameters in critically ill patients.

One study published in the Journal of Intensive Care demonstrated that hydroxyethyl starch solutions were associated with a significant increase in mean arterial pressure and cardiac index compared to crystalloid solutions in patients with septic shock.

Additional Information

It is important to monitor patients receiving Refordez-Novofarm for signs of fluid overload, renal impairment, and coagulopathy. The use of hydroxyethyl starch solutions has been associated with adverse effects such as renal dysfunction and coagulopathy, especially in patients with pre-existing renal impairment.

Before using Refordez-Novofarm, healthcare providers should carefully assess the patient’s fluid status, renal function, and overall clinical condition to determine the appropriateness of treatment with hydroxyethyl starch solution.