Description

Refortan N GEK (hydroxyethyl starch) solution for infusion 6% 500 ml. №1 vial

Ingredients

Active ingredient: Hydroxyethyl starch

Dosage

Dosage: The dosage of Refortan N GEK solution for infusion should be individualized based on the patient’s condition and response to treatment. It is typically administered intravenously over a specific period as directed by a healthcare professional.

Indications

Indications: Refortan N GEK is indicated for the treatment of hypovolemia (low blood volume) and shock to restore and maintain adequate blood pressure and tissue perfusion.

Contraindications

Contraindications: Refortan N GEK is contraindicated in patients with known hypersensitivity to hydroxyethyl starch, severe renal impairment, severe coagulopathy, and in patients with intracranial bleeding.

Directions

Directions: Refortan N GEK solution for infusion should be administered by healthcare professionals experienced in fluid and electrolyte management. The infusion rate and total volume administered should be carefully monitored.

Scientific Evidence

Pharmacological Effects: Hydroxyethyl starch solutions like Refortan N GEK work by expanding plasma volume, which helps improve hemodynamic parameters and tissue perfusion. This can be beneficial in conditions such as hypovolemia and shock.

Clinical Trials: Several studies have evaluated the efficacy and safety of hydroxyethyl starch solutions in various clinical settings. A systematic review by Joosten et al. (2018) found that hydroxyethyl starch solutions were effective in increasing intravascular volume and improving hemodynamic stability in critically ill patients.

Additional Information

It is important to monitor patients receiving Refortan N GEK for signs of volume overload, renal impairment, and coagulopathy. Close monitoring of vital signs and laboratory parameters is essential during treatment with hydroxyethyl starch solutions.

Before using Refortan N GEK, healthcare providers should carefully assess the patient’s clinical condition, fluid status, and the risks and benefits of treatment to ensure safe and appropriate use of the medication.