Sanorin (naphazoline nitrate) nasal spray 0.5 mg/ml. 10 ml. vial

Description

Sanorin (naphazoline nitrate) nasal spray 0.5 mg/ml. 10 ml. vial

Composition

Pharmacological properties

Naphazoline is a drug that stimulates the sympathetic nervous system and acts on -adrenoceptors, has minimal effect on β-adrenoceptors. Due to the vasoconstrictive effect, edema, hyperemia, and exudation are reduced, which facilitates nasal breathing in rhinitis. Nafazolin promotes the opening and expansion of the outlet ducts of the paranasal sinuses and Eustachian tubes, which improves the outflow of secretions and prevents the deposition of bacteria.
The therapeutic effect of intranasal use occurs within 5 minutes and lasts 4‒6 hours.

Indication

Acute rhinitis. As an aid in inflammation of the paranasal sinuses and middle ear.

Contraindication

Hypersensitivity to the active substance or to any component of the drug.
Dry inflammation of the nasal mucosa.
Do not use in children under 3 years.

Method of application and dosage

For children aged 3 to 6 years, apply 1-2 irrigations in each nasal passage, for children aged 6 to 15 years – 2 irrigations in each nasal passage.

Apply Sanorin spray 3 times a day, but not more often than after 4 hours.

Sanorin spray should not be used for more than 3 days.

If nasal breathing improves, you can stop the use earlier.

You can reapply Sanorin spray only after a few days.

Children

Apply to children from 3 years.

Overdose

Overdose or accidental ingestion of the drug can cause systemic side effects: nervousness, sweating, headache, tremor, tachycardia, palpitations, hypertension. Cyanosis, nausea, fever, spasms, cardiac arrest, pulmonary edema, mental disorders, pale skin, heart attack may occur.
Depressant effect on the central nervous system is manifested by symptoms such as fever, bradycardia, sweating, drowsiness, shock, similar to hypotension, apnea, coma. The risk of overdose increases in children who are more vulnerable to adverse effects than adults.
Treatment is symptomatic.

Side effects

In patients with hypersensitivity, the drug may occasionally cause burning and dryness of the nasal mucosa. In isolated cases, a feeling of severe nasal congestion may occur.
Only in isolated cases there is a systemic side effect (most often in case of overdose):

• From the immune system: allergic reactions, including Quincke’s edema, burning.
• From the nervous system: nervousness, headache, tremor.
• From the cardiac system: tachycardia, palpitations.
• From the vascular system: hypertension.
• From the skin and subcutaneous tissue: increased sweating.

Prolonged or frequent use of the drug can lead to addiction – sanorinism, accompanied by intense swelling of the nasal mucosa, which occurs in a relatively short period of time after application. Prolonged use of the drug can damage the epithelium of the mucous membrane, inhibit the activity of the epithelial cilia and cause irreversible damage to the mucous membrane and the development of dry rhinitis.