Description
Sedalgyn Plus (metamizole, caffeine, thiamine) Tablets №20
Ingredients
- Each tablet contains:
- Metamizole 500mg
- Caffeine 50mg
- Thiamine 10mg
Dosage
- Adults: Take 1-2 tablets every 6 hours as needed.
- Do not exceed 8 tablets in 24 hours.
- Consult a healthcare professional for children’s dosages.
Indications
- Sedalgyn Plus tablets are indicated for the relief of mild to moderate pain, including headaches, toothaches, and menstrual cramps.
Contraindications
- Do not use Sedalgyn Plus tablets if you have a history of hypersensitivity to any of the ingredients.
- Avoid if you have a history of agranulocytosis with other pyrazolone derivatives.
Directions
- Take the tablets orally with water.
- Do not crush or chew the tablets.
- Follow the recommended dosage and do not exceed the stated dose.
Scientific Evidence
- Studies suggest that the combination of metamizole, caffeine, and thiamine in Sedalgyn Plus tablets provides effective pain relief.
- Compared to traditional NSAIDs, Sedalgyn Plus has a reduced risk of gastrointestinal side effects.
- The synergistic action of these ingredients targets pain pathways and enhances pain relief.
Additional Information
- Sedalgyn Plus tablets offer a convenient and effective option for managing various types of pain.
- Caffeine enhances the analgesic effect and improves alertness and reduces fatigue.
- Thiamine supports nerve health and function, complementing the pain-relieving properties of metamizole and caffeine.
Pharmacological Actions:
- Metamizole acts as a non-opioid analgesic by inhibiting prostaglandin synthesis, reducing pain and inflammation.
- Caffeine, a CNS stimulant, enhances the analgesic effect of metamizole.
- Thiamine, a water-soluble vitamin, supports nerve function and may help alleviate neuropathic pain.
Clinical Trials:
- Clinical trials have shown the efficacy of Sedalgyn Plus in providing rapid and sustained pain relief.
- It is a valuable option for effective pain management with a favorable safety profile.





