Description

Sodiofolin (Disodium Folinate) Solution for Injections or Infusions 400 mg. 50 mg/ml. 8 ml. №1 Vial

Ingredients:

Sodiofolin (Disodium Folinate) solution contains 400 mg of disodium folinate per 8 ml vial.

Dosage:

The recommended dosage of Sodiofolin solution for injections or infusions is determined by the healthcare provider based on the patient’s condition and needs.

Indications:

Sodiofolin is indicated for use in combination with certain chemotherapy drugs to reduce the toxic effects on healthy cells and enhance the efficacy of the treatment.

Contraindications:

Do not use Sodiofolin if there is a known hypersensitivity to folinic acid or any component of the product.

Directions:

Sodiofolin should be administered as directed by a healthcare professional experienced in the use of chemotherapy agents.

Scientific Evidence:

Sodiofolin, a form of folinic acid, plays a crucial role in DNA synthesis and repair. By providing an exogenous source of folate, Sodiofolin helps maintain the necessary building blocks for cell division, especially in rapidly dividing cells like those found in cancer. Several studies have demonstrated the efficacy of folinic acid in reducing the toxic effects of methotrexate, a commonly used chemotherapy agent, without compromising its antitumor activity.

Research by Mhaidat et al. (2018) showed that the addition of folinic acid to methotrexate therapy significantly reduced the incidence and severity of mucositis and gastrointestinal toxicity in cancer patients. This highlights the importance of Sodiofolin in improving the tolerability and outcomes of chemotherapy.

Additional Information:

• Storage: Store Sodiofolin solution at the recommended temperature to maintain its stability and efficacy.
• Side Effects: Common side effects may include nausea, vomiting, and allergic reactions. Consult a healthcare provider for more information.