Description

Soleron 100 (amisulpride) tablets 100 mg. №30

Ingredients

Active ingredient: Amisulpride 100 mg per tablet.

Dosage

Recommended dosage: The usual dose is 100 mg once daily. Dosage may vary based on individual needs and as directed by a healthcare professional.

Indications

Soleron 100 tablets are indicated for the treatment of schizophrenia.

Contraindications

Do not use Soleron 100 tablets if you are allergic to amisulpride or any other ingredients in the product. Consult a healthcare provider before use if you have a history of certain medical conditions.

Directions

Take Soleron 100 tablets orally with or without food, as directed by your healthcare provider. Swallow the tablet whole with a full glass of water.

Scientific Evidence

Amisulpride, the active ingredient in Soleron 100 tablets, is an atypical antipsychotic agent that primarily works by blocking dopamine D2 and D3 receptors in the brain. This mechanism helps to regulate dopamine levels, which are often imbalanced in individuals with schizophrenia. Several studies have shown the efficacy of amisulpride in managing symptoms of schizophrenia, including positive and negative symptoms, with a favorable side effect profile.

Additional Information

It is important to follow the prescribed dosage and duration of treatment with Soleron 100 tablets to achieve the best therapeutic outcomes. Regular monitoring by a healthcare provider is recommended to assess the response to treatment and adjust the dosage if needed.

Pharmacological Effects

Amisulpride exerts its pharmacological effects by selectively blocking dopamine receptors in the brain, particularly the D2 and D3 receptors. By modulating dopamine activity, amisulpride helps to alleviate symptoms of schizophrenia such as hallucinations, delusions, and disorganized thinking. Additionally, its minimal affinity for other receptors reduces the risk of certain side effects commonly associated with typical antipsychotic medications.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of amisulpride in the treatment of schizophrenia, showing improvements in both positive and negative symptoms compared to placebo. Furthermore, comparative studies have suggested that amisulpride may offer advantages in terms of tolerability and side effect profile when compared to other antipsychotic agents. Research by Leucht et al. (2013) highlighted the favorable risk-benefit profile of amisulpride in the management of schizophrenia.

• Leucht S, Cipriani A, Spineli L, et al. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet. 2013 Sep 14;382(9896):951-62.