Description

Terbinorm (Terbinafine) Spray 10.08 mg/ml. 20 ml Vial

Ingredients

Terbinafine is the active ingredient in Terbinorm spray, present in a concentration of 10.08 mg/ml. It is a potent antifungal agent that works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes.

Dosage

The recommended dosage of Terbinorm spray is to apply a thin layer to the affected area twice daily. It is important to clean and dry the area before application to ensure optimal absorption of the medication.

Indications

Terbinorm spray is indicated for the treatment of fungal infections of the skin, such as athlete’s foot, jock itch, and ringworm. It effectively targets the fungus, providing relief from itching, burning, and discomfort associated with these conditions.

Contraindications

Do not use Terbinorm spray if you are allergic to terbinafine or any other ingredients in the formulation. It is important to consult a healthcare provider before use, especially if you have a history of liver or kidney disease.

Directions

For external use only, shake the vial well before use. Hold the spray bottle 4 inches away from the skin and spray the affected area. Wash hands after application. Avoid contact with eyes, mouth, and mucous membranes.

Scientific Evidence

Studies have shown the efficacy of terbinafine in treating fungal skin infections. Research published in the Journal of the American Academy of Dermatology demonstrated the superior clinical cure rates of terbinafine compared to other antifungal agents.

Additional Information

It is important to complete the full course of treatment as prescribed by your healthcare provider, even if symptoms improve before the treatment is finished. Failure to do so may result in the recurrence of the infection. Keep the spray away from heat and flame, and store it at room temperature.

Pharmacological Effects: Terbinafine exerts its antifungal effects by specifically inhibiting the enzyme squalene epoxidase, disrupting the synthesis of ergosterol in fungal cell membranes. This action leads to increased membrane permeability and ultimately fungal cell death.

Clinical Trials: Clinical trials have demonstrated the efficacy and safety of terbinafine in the treatment of various fungal infections. A study published in the British Journal of Dermatology showed a high cure rate and low recurrence rate in patients treated with terbinafine for fungal skin infections.