Tetracicline (tetracycline hydrochloride) ointment 3% 15 g. tube

Description

Tetracicline (tetracycline hydrochloride) ointment 3% 15 g. tube

Composition

active substance: tetracycline hydrochloride;

1 g of ointment contains tetracycline hydrochloride 0.03 g;

Excipients: lanolin, paraffin, ceresin, sodium metabisulfite (E 223), white soft paraffin.

Dosage form

Ointment.

Main physical and chemical properties: yellow ointment.

Pharmacotherapeutic group

Dermatological agents. Antibiotic for topical use.
ATX code D06A A04.

Pharmacological properties

Bacteriostatic broad-spectrum antibiotic from the group of tetracyclines. Disrupts the formation of a complex between transport RNA and ribosome, which leads to disruption of protein synthesis. Active against Propionibacterium acnes (Corynebacterinum acnes), gram-positive (Streptococcus spp., Staphylococcus spp., Haemophilus influenzae, Listeria spp., Bacillus anthracis) and gram-negative microorganisms (Neisseria gonorppoliascaris, Neisseria gonorrholatericlaea, Neisseria gonorrholaterica, Esis Salmonella spp., Shigella spp.), As well as Rickettsia spp., Chlamidia spp., Mycoplasma spp., Treponema spp. Resistant to the drug: Pseudomonas aeruginosa, Proteus spp., Serratia spp., Most strains of Bacteroides spp. and fungi, small viruses.

Indications

Tetracicline ointment is used in therapy of inflammatory and infectious diseases caused by tetracycline-sensitive microflora, such as bronchitis, pneumonia, tonsillitis, pleural empyema, cholecystitis, pyelonephritis, intestinal infection, endometritis, endocarditis, syphilis, prostatitis, brucellosis, gonorrhea, pus rickettsioses, trachoma, osteomyelitis, blepharitis, conjunctivitis, acne.
In addition, the drug is used to prevent the development of postoperative infectious complications.

Contraindications

Tetracycline is not prescribed for patients who have been identified as hypersensitive to tetracycline hydrochloride and related antibiotics. The drug is not used in the treatment of fungal infections and is not prescribed for pregnant and lactating women.
Particular care should be taken when prescribing the drug to patients who have renal failure, leukopenia and have a history of allergic reactions.
Due to the fact that strains resistant to tetracycline have been widespread recently, the drug is used very rarely.
Tetracycline is not used for children under 8 years of age because it can cause permanent discoloration of the tooth enamel.
When taking tetracycline for the prevention of hypovitaminosis, patients should take vitamins of groups K and B.
At the time of treatment with Tetracycline, the patient should refuse to use dairy products, since they prevent the adsorption of the antibiotic.

Application during pregnancy and lactation

Due to the fact that tetracycline hydrochloride is able to penetrate the placental barrier and cause hypoplasia of tooth enamel, inhibit the growth of bones of the fetal skeleton and change the color of the teeth for a long time and cause the development of fatty infiltration of the liver tissue, the use of tetracycline in the therapy of women at the stage of lactation and pregnancy is impossible.

Method of administration and dosage

When using the drug in the form of an ointment, it is applied with a thin layer on the affected skin area from 3 to 5 times per knocking. If necessary, it is possible to apply an ointment under a weak bandage.

Overdose

With oral administration of tetracycline in high doses, patients experience increased side effects. With local application of the drug, an overdose is impossible.

Side effects

In some patients, when taking tetracycline, there is the development of nausea, vomiting, abdominal pain, anorexia, stool disorders, dry mouth, glossitis, esophagitis, discoloration of teeth and tongue, increased activity of liver enzymes, dizziness, headaches, anemia, photosensitization and allergic reactions.