Thiotriazolin (thiazotic acid) tablets 200 mg. №90

Description

Thiotriazolin (thiazotic acid) tablets 200 mg. №90

Composition

active substance: thiazotic acid;

1 tablet contains morpholinium salt of thiazotic acid in terms of 100% of the substance – 200 mg, which is equivalent to 133 mg of thiazotic acid;

Excipients: potato starch, povidone, powdered sugar, microcrystalline cellulose, calcium stearate.

Dosage form

Tablets.

Main physical and chemical properties: tablets of white or almost white color, round shape with a flat surface, chamfered and dashed.

Pharmacotherapeutic group

Cardiac drugs. Other cardiac drugs. Thiazotic acid.
ATX code C01E B23.

Pharmacological properties

It is a remedy that improves metabolic processes. It has anti-ischemic, membrane stabilizing, antioxidant, immunomodulatory effects. The influence of the active component is realized by increasing the compensatory activation of anaerobic glycolysis, activating the oxidation process in the Krebs cycle while maintaining the ATP fund in the cell. It inhibits the processes of fat oxidation in the ischemic area of ​​the heart muscle, reduces its sensitivity to catecholamines, prevents the progression of contraction of the contractile function of the heart, and reduces the zone of myocardial necrosis.

Indications

Thiotriazolin tablets is used:

• in the complex treatment of coronary heart disease: myocardial infarction, angina pectoris, postinfarction cardiosclerosis;
• in the complex treatment of cardiac arrhythmias;
• in the complex treatment of chronic hepatitis (cryptogenic, alcoholic), liver fibrosis, liver cirrhosis.

Contraindications

Thiotriazolin tablets is contraindicated:

• with intolerance to the components of the drug;
• with severe renal impairment.

Application during pregnancy and lactation

The experience of using Thiotriazolin during these periods is insufficient.

Method of administration and dosage

Thiotriazolin tablets are used orally.
Standard doses for stable exertional angina are 200 mg 3 times / day. The course is 8 weeks.
Standard doses for myocardial infarction, rest angina, postinfarction cardiosclerosis – 200 mg 3 times / day for 20-30 days.
Standard doses for cardiac arrhythmias are 200 mg orally or under the tongue 3 times / day.
For liver disease – 200 mg orally 3 times / day for 20-30 days.
The duration of the course is individual – depending on the severity of the disease.

Overdose

Signs of an overdose: an increase in the concentration of sodium, potassium in the urine.
In case of an overdose, the drug is canceled, symptomatic treatment is prescribed.

Side effects:

• Cardiovascular disorders: decrease / increase in blood pressure, palpitation, tachycardia.
• Neurological disorders: headaches, tinnitus, dizziness, coordination disorders.
• Digestive disorders: dry mouth, nausea, flatulence, dyspepsia.
• Immune disorders: manifestations of allergies, including skin rashes, urticaria, angioedema, itching.
• Others: choking, shortness of breath, fever, weakness.