Description

Tramix (Tranexamic Acid) Solution for Injections 100 mg/ml. 5 ml. Vials №5

Ingredients

Active ingredient: Tranexamic acid. Inactive ingredients may include water for injection.

Dosage

Dosage: The usual dose of Tramix for adults is 1 gram (10 ml) by slow intravenous injection, to be repeated if necessary. Dosage may vary based on the condition being treated. Consult a healthcare professional for the appropriate dosage.

Indications

Indications: Tramix is indicated for the treatment of heavy menstrual bleeding, prevention of excessive bleeding during surgery, and management of bleeding disorders.

Contraindications

Contraindications: Do not use Tramix if you have a history of blood clots, color vision disorders, or if you are allergic to tranexamic acid. Consult a healthcare provider for a full list of contraindications.

Directions

Directions: Tramix is for intravenous use only. It should be administered by a healthcare professional in a clinical setting. Follow the instructions provided by your healthcare provider.

Scientific Evidence

Tranexamic acid, the active ingredient in Tramix, works by inhibiting the breakdown of blood clots, thereby reducing bleeding. Studies have shown that tranexamic acid is effective in reducing blood loss during surgery and in the treatment of heavy menstrual bleeding. Research published in the Journal of Thrombosis and Haemostasis supports the efficacy of tranexamic acid in various clinical settings.

Additional Information

Tramix is a well-tolerated medication with a good safety profile when used as directed. It is important to inform your healthcare provider about any medications you are currently taking to avoid potential drug interactions. Store Tramix at the recommended temperature and out of reach of children.

Pharmacological Effects: Tranexamic acid exerts its pharmacological action by blocking the lysine binding sites on plasminogen molecules. This inhibition prevents the conversion of plasminogen to plasmin, thereby reducing fibrinolysis and promoting clot stability.

Clinical Trials: Clinical trials have demonstrated the efficacy of tranexamic acid in various medical conditions, including trauma, postpartum hemorrhage, and orthopedic surgery. A study published in the British Journal of Surgery showed that tranexamic acid significantly reduced blood loss and the need for blood transfusions in patients undergoing total knee arthroplasty.