Description

Trenaxa 500 (Tranexamic Acid) Coated Tablets 500 mg. №12

Ingredients

Active ingredient: Each coated tablet contains 500 mg of Tranexamic Acid.

Dosage

Dosage: The usual dosage is 1-1.5 grams daily in divided doses for up to 4 days during menstruation.

Indications

Indications: Trenaxa 500 is indicated for the treatment of heavy menstrual bleeding (menorrhagia) in women.

Contraindications

Contraindications: Do not use Trenaxa 500 if you have a history of blood clots or if you are allergic to tranexamic acid.

Directions

Directions: Swallow the tablets whole with water. Do not crush or chew the tablets.

Scientific Evidence

Tranexamic acid, the active ingredient in Trenaxa 500, works by inhibiting the breakdown of blood clots, thereby reducing heavy menstrual bleeding. Several studies have demonstrated the efficacy of tranexamic acid in significantly reducing menstrual blood loss and improving quality of life in women with menorrhagia. Research published in the “American Journal of Obstetrics and Gynecology” has shown that tranexamic acid is a safe and effective treatment for heavy menstrual bleeding.

Additional Information

It is important to follow the prescribed dosage and duration of treatment with Trenaxa 500 as directed by your healthcare provider. Inform your doctor about any other medications you are taking before starting Trenaxa 500 to avoid potential drug interactions.

Pharmacological Effects

Tranexamic acid exerts its pharmacological effects by blocking the conversion of plasminogen to plasmin, an enzyme that degrades fibrin clots. By inhibiting this process, tranexamic acid helps to stabilize blood clots and reduce excessive bleeding. This mechanism of action makes it a valuable option for managing conditions characterized by abnormal bleeding, such as menorrhagia.

Clinical Trials and Comparative Effectiveness

Clinical trials have shown that tranexamic acid is as effective as other treatments for heavy menstrual bleeding, with the added benefit of being well-tolerated and convenient to use. Compared to hormonal therapies or surgical interventions, tranexamic acid offers a non-invasive and cost-effective approach to managing menorrhagia. Studies have also indicated that tranexamic acid may have a faster onset of action and fewer side effects compared to other treatments, making it a preferred choice for many women.

• Tranexamic acid inhibits the breakdown of blood clots.
• Studies have shown its efficacy in reducing menstrual blood loss.
• It is a safe and well-tolerated treatment for menorrhagia.