Troxerutin-Darnitsa (troxerutin) gel 2% 30 g. tube

Description

Troxerutin-Darnitsa (troxerutin) gel 2% 30 g. tube

Composition

active ingredient: troxerutin;

1 g of gel contains troxerutin 20 mg;

excipients: methyl parahydroxybenzoate (E 218), propylene glycol, carbomer 980, trometamol, disodium edetate, purified water.

Dosage form

Gel.

Basic physical and chemical properties: transparent yellow gel with a slight characteristic odor. It must be uniform in appearance.

Pharmacotherapeutic group

Angioprotectors. capillary stabilizing agents. Troxerutin.
ATX code C05C A04.

Pharmacological properties

This drug Troxerutin-Darnitsa is a drug from the group of capillary stabilizing agents, which is used systemically.
Troxerutin, which is the active ingredient of the drug, belongs to the group of bioflavonoids. It has an angioprotective effect, can cause a decrease in the permeability and fragility of small blood vessels, protecting their walls, and produces a pronounced venotonic, antioxidant, anti-inflammatory, decongestant and capillary-protective effect.
Thanks to the action of troxerutin, the capillaries restore the properties of elasticity, resilience and resistance after traumatic injuries. Participates in the synthesis of collagen. It has the property of improving the quality indicators of blood (harmonizes its viscosity).
Able to eliminate the vasodilating effect of histamines, bradykinins and acetylcholines. It has antiplatelet and anti-inflammatory properties in relation to paravenous tissues, causing an increase in capillary sensitivity.
It helps to reduce puffiness and other congestion in veins and tissues, and also has the property of improving their trophism in cases where pathological changes have occurred in them, the cause of which is venous insufficiency.

Indications

Troxerutin-Darnitsa is intended for the symptomatic treatment of:

•  venous insufficiency;
•  varicose veins;
•  superficial thrombophlebitis, phlebitis, conditions after phlebitis;
•  rheumatism of soft tissues – tendovaginitis, bursitis, fibrositis, periarthritis;
•  edema after surgery;
•  bruises, dislocations, sprains, cramps of the calf muscles (cramps).

It can also be used in the complex therapy of hemorrhoids.

Contraindications

The drug in question is not used if the patient has ever had hypersensitivity (allergy) to one of the components that make up its composition.
It is also contraindicated for use in bronchial asthma, since the drug can cause bronchospasm in those suffering from this disease.
Do not apply to areas of skin affected by eczema.
This drug is not used together with other non-steroidal anti-inflammatory drugs, as this can cause a potentiation of the effect, as well as with corticosteroids, as this can cause the likelihood of an ulcerogenic effect.
It is advisable not to use it in pediatrics.

Application during pregnancy and lactation

This drug is contraindicated for the treatment of pregnant women.
Lactation is suspended for the duration of treatment with this drug.

Method of administration and dosage

Troxerutin-Darnitsa is applied as a thin layer on the skin over the painful area, rubbing it into the skin with light circular movements for 1-2 minutes.
It is applied twice a day – in the morning and in the evening. If necessary, it is permissible to make a bandage over the applied gel using an elastic bandage or wear tight-fitting stockings.
The duration of the treatment course is determined by the attending physician, depending on the symptoms and individual tolerance of the drug.
Usually the course of treatment lasts from 1 to 1.5 months. If the disease recurs, the course of treatment can be repeated 2-3 times a year.
In severe cases, it is recommended to take troxerutin orally, in capsule form.
Care should be taken to ensure that the drug does not get on the mucous membranes, especially the eyes.

Overdose

An overdose of this drug is unlikely, since when applied topically, this drug has practically no effect on the systemic circulation.
At the same time, if used for too long, the drug can cause symptoms of hepatotoxicity in the form of headaches, hemorrhages.
Accidental swallowing may cause burning mouth, drooling and nausea, and at high doses, vomiting.
If this happens, you should rinse the stomach, induce vomiting, take enterosorbents.
Contact with mucous membranes can cause flushing, burning, pain.
In this case sodium chlorine is used to wash off the gel.

Side effects

The use of this drug can cause side reactions, usually of a local nature:

•  contact dermatitis, itching, redness;
•  rash, feeling of warmth and burning at the site of application.

Long-term use can cause systemic reactions in the form of:

•  nausea, vomiting;
•  stomach pain;
•  increasing levels of liver enzymes;
•  hypersensitivity (anaphylactic shock, angioedema);
•  an attack of bronchial asthma.

If any adverse reactions occur, you should stop using the drug and always consult a doctor.