Description

Zanidip (lercanidipine hydrochloride) Coated Tablets 10 mg. №28

Ingredients:

Each coated tablet contains 10 mg of lercanidipine hydrochloride as the active ingredient. Other ingredients include lactose monohydrate, maize starch, povidone, magnesium stearate, macrogol, hypromellose, talc, titanium dioxide (E171), and red and yellow iron oxides (E172).

Dosage:

The usual dose is one tablet daily, preferably to be taken in the morning before breakfast. The tablet should be swallowed whole with a sufficient amount of water.

Indications:

Zanidip tablets are indicated for the treatment of essential hypertension in adults. It helps to lower high blood pressure, reducing the risk of heart attacks, strokes, and kidney problems.

Contraindications:

Do not take Zanidip if you are allergic to lercanidipine or any other ingredients in the tablets. It is contraindicated in patients with severe liver or kidney problems, pregnant or breastfeeding women, and children.

Directions:

Follow the instructions provided by your healthcare provider. It is important to take Zanidip regularly to get the most benefit from it. Do not stop taking the medication without consulting your doctor.

Scientific Evidence:

Zanidip (lercanidipine hydrochloride) has shown significant efficacy in lowering blood pressure in clinical studies. Research published in the European Heart Journal demonstrated that lercanidipine effectively reduces both systolic and diastolic blood pressure levels, with a good tolerability profile.

Additional Information:

Zanidip belongs to the class of calcium channel blockers, which work by relaxing and widening the blood vessels, making it easier for the heart to pump blood. This action helps to lower blood pressure and improve blood flow to the heart.

Compared to other calcium channel blockers, lercanidipine has a longer duration of action, allowing for once-daily dosing and better compliance. It has also been associated with a lower incidence of peripheral edema, a common side effect of this drug class.