Description
Zoladex (Gozerelin) Capsules for Subcutaneous Use 10.8 mg
Ingredients:
- Zoladex contains 10.8 mg of gozerelin acetate as the active ingredient.
- Other ingredients include lactide/glycolide copolymer, D-mannitol, and carboxymethylcellulose sodium.
Dosage:
The recommended dosage of Zoladex is one 10.8 mg capsule administered subcutaneously every 28 days using the syringe applicator provided.
Indications:
- Zoladex is indicated for the palliative treatment of advanced prostate cancer.
- It is also used in the treatment of endometriosis and certain breast cancers.
Contraindications:
- Do not use Zoladex if you are pregnant, breastfeeding, or allergic to gozerelin acetate or any other ingredients in the product.
Directions:
Administer Zoladex exactly as prescribed by your healthcare provider. Follow the instructions for subcutaneous injection carefully.
Scientific Evidence:
Studies have shown that Zoladex effectively suppresses the production of certain hormones, leading to tumor regression in hormone-sensitive cancers. Research published in the Journal of Clinical Oncology demonstrated the efficacy of Zoladex in improving survival rates in prostate cancer patients.
Additional Information:
- It is important to store Zoladex in the refrigerator between 36°F to 46°F (2°C to 8°C) and protect it from light.
- Always consult your healthcare provider for personalized advice on using this medication.
Pharmacological Effects: Zoladex belongs to a class of medications known as gonadotropin-releasing hormone (GnRH) agonists. It works by continuously suppressing the production of certain hormones, thereby inhibiting the growth of hormone-sensitive tumors.
Clinical Trials: Clinical trials have demonstrated the efficacy of Zoladex in various conditions. A study published in the European Journal of Cancer evaluated the use of Zoladex in breast cancer treatment and reported positive outcomes in terms of tumor response and patient survival rates.
