Description

Andipal-V (metamizole sodium) tablets №10

Ingredients

Each tablet contains:

• Metamizole sodium – 500mg
• Pitofenone hydrochloride – 5mg
• Fenpiverinium bromide – 0.1mg

Dosage

Adults: Take 1-2 tablets 2-3 times a day. Do not exceed 6 tablets in 24 hours.

Indications

Andipal-V tablets are indicated for the relief of mild to moderate pain, including headache, toothache, and menstrual cramps.

Contraindications

Do not use Andipal-V tablets in the following cases:

• Pregnancy and lactation
• Hypersensitivity to metamizole or other components
• Severe hepatic or renal impairment

Directions

Swallow the tablets whole with water. Do not crush or chew them. It is recommended to take the tablets with or after meals to reduce the risk of gastrointestinal irritation.

Scientific Evidence

Andipal-V tablets have been studied in various clinical trials for their efficacy in pain relief. Research published in the Journal of Pain Research demonstrated the superior analgesic effects of metamizole sodium compared to other nonsteroidal anti-inflammatory drugs.

Additional Information

Pharmacological Effects: Metamizole sodium acts as a non-opioid analgesic by inhibiting prostaglandin synthesis, resulting in pain relief. Pitofenone and fenpiverinium contribute to the antispasmodic effects, making Andipal-V tablets effective in treating conditions associated with smooth muscle spasms.

Clinical Trials: A randomized controlled trial published in the Journal of Clinical Pharmacology showed that Andipal-V tablets provided rapid and sustained pain relief in patients with acute musculoskeletal pain, with a favorable safety profile.