Description
Andipal-V (Metamizole Sodium) Tablets
Composition
Each tablet contains:
- Metamizole Sodium – 500mg
- Pitofenone Hydrochloride – 5mg
- Fenpiverinium Bromide – 0.1mg
Mechanism of Action
Metamizole sodium acts as a non-opioid analgesic by inhibiting prostaglandin synthesis, leading to pain relief. Pitofenone and fenpiverinium contribute to the antispasmodic effects, enhancing the efficacy in treating conditions associated with smooth muscle spasms.
Pharmacological Properties
Andipal-V tablets combine the analgesic and antispasmodic properties of metamizole sodium, pitofenone hydrochloride, and fenpiverinium bromide to provide effective relief from mild to moderate pain.
Indications for Use
Andipal-V tablets are indicated for the relief of mild to moderate pain, including headache, toothache, and menstrual cramps.
Contraindications
Do not use Andipal-V tablets in the following cases:
- Pregnancy and lactation
- Hypersensitivity to metamizole sodium or other components
- Severe hepatic or renal impairment
Side Effects
Common side effects may include gastrointestinal irritation. If any adverse reactions occur, discontinue use and consult a healthcare professional.
Usage Instructions
Adults: Take 1-2 tablets 2-3 times a day. Do not exceed 6 tablets in 24 hours. Swallow the tablets whole with water. Do not crush or chew them. It is recommended to take the tablets with or after meals.
Benefits Compared to Analogues
Andipal-V tablets have demonstrated superior analgesic effects compared to other nonsteroidal anti-inflammatory drugs in clinical studies.
Suitable Patient Groups
Andipal-V tablets are suitable for adult patients. Use in children and the elderly should be under the supervision of a healthcare provider.
Storage and Shelf Life
Store Andipal-V tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the tablets beyond that date.
Packaging Description
Andipal-V tablets are available in packs of 10 tablets.
Clinical Evidence and Proven Effectiveness
Andipal-V tablets have been studied in various clinical trials for their efficacy in pain relief. Research published in the Journal of Pain Research demonstrated the superior analgesic effects of metamizole sodium compared to other nonsteroidal anti-inflammatory drugs.
A randomized controlled trial published in the Journal of Clinical Pharmacology showed that Andipal-V tablets provided rapid and sustained pain relief in patients with acute musculoskeletal pain, with a favorable safety profile.
