Description

Celoda (capecitabine) Coated Tablets 150 mg. №60

Ingredients

Each coated tablet contains 150 mg of capecitabine.

Dosage

The recommended dosage of Celoda is determined by the patient’s body surface area and the specific treatment regimen. It is crucial to follow the prescribed dosage and administration instructions provided by a healthcare professional.

Indications

Celoda is indicated for the treatment of various types of cancer, including breast, colorectal, and gastric cancers. It is used either alone or in combination with other chemotherapy medications.

Contraindications

Celoda is contraindicated in patients with known hypersensitivity to capecitabine or any of the excipients in the formulation. It should not be used in patients with severe renal impairment or dihydropyrimidine dehydrogenase (DPD) deficiency.

Directions

Celoda tablets should be taken with water within 30 minutes after a meal. The dosage schedule may vary based on the treatment regimen. It is important to swallow the tablets whole and not crush or chew them.

Scientific Evidence

Celoda (capecitabine) is a prodrug that is enzymatically converted to 5-fluorouracil (5-FU) in the body. 5-FU is an antimetabolite that interferes with DNA synthesis and cell division, ultimately leading to cell death. This mechanism of action makes Celoda effective in inhibiting the growth of cancer cells.

Clinical trials have demonstrated the efficacy of Celoda in various cancer types, showing improvements in progression-free survival and overall survival rates. Additionally, studies have highlighted the favorable safety profile of Celoda compared to traditional intravenous 5-FU regimens.

Additional Information

It is essential for patients taking Celoda to undergo regular monitoring of blood counts and liver function tests due to the potential side effects of the medication. Common side effects may include hand-foot syndrome, diarrhea, nausea, and fatigue.

Patients should inform their healthcare provider about any existing medical conditions and medications they are taking before starting Celoda therapy to prevent potential drug interactions or adverse effects.