Description

Diclofenak (diclofenac) gel 5% 50 g. tube

Ingredients

Diclofenac Sodium 5% is the active ingredient in Diclofenak gel. Other inactive ingredients include carbomer, cocoyl caprylocaprate, diethylamine, isopropyl alcohol, liquid paraffin, and perfume.

Dosage

Apply a thin layer of Diclofenak gel to the affected area 3 to 4 times daily. Gently massage the gel into the skin. Wash hands after application.

Indications

Diclofenak gel is indicated for the relief of pain and inflammation associated with musculoskeletal conditions such as arthritis, sprains, strains, and backache.

Contraindications

Do not use Diclofenak gel if you are allergic to diclofenac or other NSAIDs, have a history of asthma attacks, hives, or other allergic reactions after taking aspirin or other NSAIDs.

Directions

Clean and dry the affected area before applying Diclofenak gel. Avoid contact with eyes, mucous membranes, or open wounds. Do not bandage or wrap the treated area.

Scientific Evidence

Studies have shown that topical diclofenac formulations like Diclofenak gel can provide effective pain relief with lower systemic exposure compared to oral NSAIDs. The gel formulation allows for targeted delivery to the site of pain, reducing the risk of systemic side effects.

Additional Information

It is important to follow the recommended dosage and frequency of application to avoid overdose or skin irritation. If symptoms persist or worsen, discontinue use and consult a healthcare professional.

Diclofenak gel works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins that cause pain and inflammation. This localized action helps to alleviate pain without affecting the entire body system.

Comparative studies have shown that topical diclofenac formulations are as effective as oral NSAIDs in managing pain and inflammation in conditions like osteoarthritis and soft tissue injuries. The advantage of topical gels is their targeted action with minimal systemic absorption, reducing the risk of gastrointestinal side effects.