Description
Diclofenak natrium (diclofenac) 2.5% 3 ml. №5
Ingredients
Diclofenac sodium 2.5% is the active ingredient in this pharmaceutical product. Other ingredients may include preservatives and stabilizers.
Mechanism of Action
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. It works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins that cause pain and inflammation.
Pharmacological Properties
Diclofenac gel exhibits anti-inflammatory, analgesic, and antipyretic properties. It effectively reduces pain and inflammation at the site of application.
Indications for Use
Diclofenac gel is indicated for the relief of pain and inflammation associated with musculoskeletal conditions such as arthritis, sprains, and strains.
Contraindications
Do not use diclofenac gel if allergic to diclofenac or other NSAIDs. Avoid contact with eyes and mucous membranes. Consult a healthcare provider before use, especially if pregnant, breastfeeding, or with a history of gastrointestinal disorders.
Side Effects
Common side effects of diclofenac gel may include skin irritation, redness, itching, or dryness at the application site. In rare cases, systemic side effects such as gastrointestinal bleeding or allergic reactions may occur.
Usage Instructions
Apply a thin layer of the gel to the affected area and gently rub in. Wash hands after application. Avoid covering the treated area with bandages or dressings. Use as directed by a healthcare professional.
Benefits Compared to Analogues
Diclofenac gel offers localized pain relief with reduced systemic absorption compared to oral NSAIDs, potentially minimizing systemic side effects. Its topical application provides targeted therapy for musculoskeletal conditions.
Suitable Patient Groups
Diclofenac gel is suitable for adults, including elderly patients, and adolescents over 14 years old. Use in children should be under medical supervision.
Storage Conditions and Shelf Life
Store diclofenac gel at room temperature away from moisture and heat. Keep out of reach of children. Check the expiration date on the packaging and do not use expired products.
Packaging Description
Diclofenac gel is available in tubes containing 3 ml of 2.5% gel. Each package typically contains 5 tubes for multiple applications.
Scientific Evidence
Clinical trials have shown the efficacy of diclofenac gel in providing pain relief and improving function in patients with osteoarthritis and other musculoskeletal conditions. A study published in the Journal of Clinical Rheumatology demonstrated the superior effectiveness of diclofenac gel compared to placebo in reducing pain intensity and improving physical function.
Additional Information
It is important to follow the prescribed dosage and not exceed the recommended duration of use to avoid potential side effects such as skin irritation or systemic absorption of the medication. Consult a healthcare professional if symptoms persist or worsen.
Diclofenac gel offers a convenient topical treatment option for localized pain relief, providing an alternative to oral NSAIDs with potentially fewer systemic side effects.
