Neurokobal (methylcobalamin) coated tablets 500 mcg. №30

Description

Neurokobal composition
Main active ingredients: 1 tablet contains 500 mcg of methylcobalamin.
Auxiliary components: microcrystalline cellulose, corn starch, povidone K 30, colloidal silicon dioxide, talc, stearic acid, ethyl cellulose, titanium dioxide, polyethylene glycol 400, Opadry coating 03F565012 brown: hypromellose, titanium dioxide, iron oxide red, polyethylene glycol.

Release form
Available in tablet form.

Pharmacological properties
Neurokobal belongs to antianemic drugs.
The active component increases the activation of the metabolism of carbohydrates, proteins and lipids, participates in the synthetic processes of labile groups, choline, methionine, nucleic acids, creatine. In addition, the drug stimulates the accumulation of sulfhydryl groups in erythrocytes.
It is a growth factor for stimulating bone marrow function, without which normoplastic erythropoiesis is impossible. The active substance normalizes the functions of the liver and nervous system, activates the blood coagulation system, increases thromboplastic activity and prothrombin.

Indications
Neurokobal is indicated for the treatment of the following diseases and conditions:

• malignant, post-hemorrhagic and iron deficiency anemias, aplastic anemia in children, alimentary anemias, as well as those caused by toxic substances and drugs, other anemias associated with vitamin B 12 deficiency, regardless of the causes of the deficiency (gastric resection, helminthic invasions, impaired absorption from intestines, pregnancy);
• polyneuritis, trigeminal neuralgia, radiculitis, causalgia, migraine, diabetic neuritis, amyotrophic lateral sclerosis, cerebral palsy, Down’s disease, alcoholic delirium;
• sprue (together with folic acid), liver disease (hepatitis, cirrhosis), radiation sickness, psoriasis, dermatitis herpetiformis, neurodermatitis, photodermatosis.

Contraindications
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components.
The drug is contraindicated for use with:

• erythremia;
• erythrocytosis;
• neoplasms with the exception of cases accompanied by megaloblastic anemia and vitamin B12 deficiency;
• acute thromboembolic diseases.

Children
The drug is not used in pediatrics.

Application during pregnancy and lactation
This drug is not recommended for pregnant women – only under strict indications determined by the attending physician.
If it is necessary to take the drug during breastfeeding, lactation is suspended.

Method of administration and dosage
The recommended daily dose is 1500 mcg (3 tablets), which is divided into three doses.
The duration of the course of treatment depends on the nature and course of the disease and is determined individually. If there is no clinical effect after continuous administration of the drug for 1 month, the drug should be discontinued.

Overdose
In case of an overdose, side effects may increase.

Side effects
The drug is usually well tolerated when used in the recommended doses.
The following reactions can be observed:

• anorexia, nausea, vomiting, diarrhea;
• irritability, headache, dizziness, migraine, severe anxiety disorders, agitation, insomnia;
• palpitations, tachycardia, heart pain;
• hypersensitivity reactions, including urticaria, anaphylactic shock, anaphylactoid reactions;
• muscle pain, joint pain;
• itching, rash, acne;
• thrombosis, hypercoagulability;
• sweating, malaise, fever.

Storage conditions and periods
Expiration date – up to 2 years from the production date indicated on the package. Storage periods should not be exceeded.
Storage temperature should not exceed 25 ° C. Temperature deviations can change the properties of the preparation, therefore it should always be stored in its original packaging.