Description

Timolol (Timolol) Eye Drops 0.5% 5 ml Vial

Ingredients

Active ingredient: Timolol Maleate 0.5%
Inactive ingredients: Benzalkonium Chloride, Sodium Chloride, Hydrochloric Acid, Sodium Hydroxide, and Water for Injection.

Dosage

Dosage: The usual dose is 1 drop of Timolol 0.5% in the affected eye(s) twice a day.

Indications

Indications: Timolol eye drops are indicated for the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Contraindications

Contraindications: Do not use Timolol if you are allergic to any of the ingredients, have asthma or severe chronic obstructive pulmonary disease (COPD), or certain heart conditions.

Directions

Directions: Wash hands before use. Tilt your head back, pull down the lower eyelid to create a pocket, and instill 1 drop. Close your eyes for 1-2 minutes. Avoid touching the dropper tip to prevent contamination.

Scientific Evidence

Timolol, a non-selective beta-adrenergic receptor antagonist, works by reducing the production of aqueous humor in the eye, thereby lowering intraocular pressure. Studies have shown that Timolol eye drops effectively reduce intraocular pressure and are considered a first-line treatment for glaucoma.

Additional Information

Timolol eye drops may cause side effects such as eye irritation, blurred vision, or bradycardia. It is important to inform your healthcare provider about any existing medical conditions or medications before using Timolol. Regular eye check-ups are recommended while using this medication.

Pharmacological Effects: Timolol acts by blocking beta-adrenergic receptors in the ciliary body of the eye, reducing the production of aqueous humor. This leads to a decrease in intraocular pressure, which is beneficial in the management of glaucoma.

Clinical Trials: Clinical trials have demonstrated the efficacy of Timolol in lowering intraocular pressure and its role in preventing optic nerve damage in patients with glaucoma. Comparative studies have shown Timolol to be as effective as other beta-blockers in managing intraocular pressure.