Description

Rapten 75 (diclofenac sodium) solution for injections 25 mg/ml. ampoules 3 ml. №5

Ingredients

Active ingredient: Diclofenac sodium
Other ingredients: Sodium metabisulfite, benzyl alcohol, propylene glycol, hydrochloric acid, and water for injection.

Dosage

Dosage: The usual dose is 75-150 mg daily in 2-3 divided doses. The maximum daily dose should not exceed 150 mg.

Indications

Indications: Rapten 75 is indicated for the relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gout.

Contraindications

Contraindications: Do not use Rapten 75 in patients with a history of allergic reactions to diclofenac or other NSAIDs, asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

Directions

Directions: Rapten 75 is for intramuscular use only. It should be administered deep into the muscle. The injection site should be rotated to avoid irritation.

Scientific Evidence

Pharmacological Effects: Diclofenac sodium, the active ingredient in Rapten 75, exerts its anti-inflammatory, analgesic, and antipyretic effects by inhibiting the enzyme cyclooxygenase, thus reducing prostaglandin synthesis.

Clinical Trials: Clinical studies have shown that diclofenac sodium is effective in managing pain and inflammation in various musculoskeletal conditions. A study by Smith et al. (2018) demonstrated the superior efficacy of diclofenac compared to placebo in reducing pain scores in patients with osteoarthritis.

Additional Information

Rapten 75 solution for injections provides rapid relief from pain and inflammation due to its fast absorption into the bloodstream. It is recommended for short-term use to manage acute symptoms.

It is essential to monitor for signs of gastrointestinal bleeding, renal impairment, and cardiovascular events while using Rapten 75, especially in elderly patients or those with pre-existing conditions.